1: J Neuroophthalmol. 2010 Jul 6; [Epub ahead of print] 

Primary Iris Neovascularization in Neurofibromatosis Type 1.

Mulholland CP, Lyons CJ, Rootman J.

*Royal Victoria Hospital Belfast, United Kingdom; daggerDepartment of
Ophthalmology, British Columbia Children's Hospital Vancouver, British Columbia.

PMID: 20613632  [PubMed - as supplied by publisher]

2: J Neuroophthalmol. 2010 Jul 6; [Epub ahead of print] 

Transient and Subclinical Horner Syndrome in Internal Carotid Artery Dissection.

Narayanan K, Griffiths PG, Pandit RJ.

Department of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne,
United Kingdom. knarayanan@blueyonder.co.uk.

PMID: 20613631  [PubMed - as supplied by publisher]

3: J Neuroophthalmol. 2010 Jul 6; [Epub ahead of print] 

Neuroretinitis With Retrobulbar Involvement.

Vaphiades MS, Wigton EH, Ameri H, Lee AG.

Departments of Ophthalmology (MSV, EHW), Neurology (MSV), and Neurosurgery (MSV)
University of Alabama at Birmingham, Birmingham, Alabama; Department of
Ophthalmology and Visual Sciences (HA, AGL), University of Texas Medical Branch,
Galveston, Texas; Department of Ophthalmology (AGL), The Methodist Hospital,
Houston, Texas; and Departments of Ophthalmology, Neurology, and Neurosurgery,
Weill Cornell Medical College (AGL), New York, New York.

Two patients with neuroretinitis are presented, both having MRI abnormalities of
the orbital portion of the optic nerve. We review previous reports of CT and MRI
findings in patients with neuroretinitis and propose a spectrum of neuroimaging
abnormalities in these patients.

PMID: 20613630  [PubMed - as supplied by publisher]

4: J Neuroophthalmol. 2010 Jun 29; [Epub ahead of print] 

Structural-Functional Dissociation in Presumed Ethambutol Optic Neuropathy.

Masvidal D, Parrish RK 2nd, Lam BL.

Bascom Palmer Eye Institute (DM, RKP, BLL), School of Medicine and Miami
Children's Hospital, University of Miami Miller, Miami, Florida.

A 55-year-old man with pulmonary Mycobacterium avium intracellulare infection
developed decreased vision to 3/200 in the right eye, and 20/200 in the left
eye, 11 months after starting ethambutol, rifampin, and isoniazid. A diagnosis
of presumed ethambutol optic neuropathy was made, and the medications were
discontinued. Visual acuity gradually improved to 20/30 and 20/70 over a period
of 34 months. Despite improved central vision and visual field, the patient
developed progressive bilateral optic disc cupping, disc pallor, and diffuse
nerve fiber layer loss on optical coherence tomography. The observed optic nerve
head structural changes in this patient did not correlate with the markedly
improved visual function. Visual improvement may occur in ethambutol optic
neuropathy despite progressive structural changes.

PMID: 20592624  [PubMed - as supplied by publisher]

5: J Neuroophthalmol. 2010 Jun 24; [Epub ahead of print] 

MRI and Positron Emission Tomography Findings in Heidenhain Variant
Creutzfeldt-Jakob Disease.

Prasad S, Lee EB, Woo JH, Alavi A, Galetta SL.

Departments of Neurology (SP, SLG), Pathology (EBL), Radiology (JHW), and
Nuclear Medicine Hospital (AA), University of Pennsylvania, Philadelphia,
Pennsylvania.

The typical presentation of Heidenhain variant Creutzfeldt-Jakob disease (CJD)
is a rapidly progressive visual loss in the setting of a relatively normal
ophthalmologic examination. At presentation, patients with this uniformly fatal
illness frequently demonstrate only minor cortical abnormalities on MRI. Here,
we document the clinical presentation and imaging results of a patient with
Heidenhain variant CJD in whom abnormalities on positron emission tomographic
imaging were more evident than changes on MRI. These changes were present in
striate cortex and visual association areas, providing clinical-anatomical
correlation with our patient's visual deficits. Nuclear imaging provides a
considerably more sensitive measure of neural dysfunction early in the course of
this disease.

PMID: 20581692  [PubMed - as supplied by publisher]

6: J Neuroophthalmol. 2010 Jun 24; [Epub ahead of print] 

Tinnitus in Fourth Nerve Palsy: An Indicator for an Intra-Axial Lesion.

Choi SY, Song JJ, Hwang JM, Kim JS.

Department of Neurology (SYC, JSK), Seoul National University College of
Medicine, Seoul National University Bundang Hospital; Eulji University College
of Medicine (SYC); and Department of Otorhinolaryngology (JJS) and Ophthalmology
(JMH), Seoul National University College of Medicine, Seoul National University
Bundang Hospital, Seoul, Republic of Korea.

Accompanying neurological symptoms and signs are diagnostic hallmarks of fourth
nerve palsy (4NP) from an intra-axial lesion. Due to the proximity of the
trochlear nucleus and fascicles to the inferior colliculus (IC), auditory
symptoms including tinnitus may occur with an intra-axial 4NP. A 53-year-old man
with hypertension and diabetes developed right 4NP with a sudden worsening of
tinnitus. MRI disclosed an infarction involving the trochlear fascicle and IC in
the left dorsal midbrain. Tinnitus may be a symptom indicating an intra-axial
lesion causing a 4NP.

PMID: 20581691  [PubMed - as supplied by publisher]