1: J Cataract Refract Surg. 2010 Mar;36(3):534; author reply 534-5. 

Limitations of Fourier-domain OCT.

Konstantopoulos A, Hossain P.

Publication Types:
    Comment
    Letter

PMID: 20202572  [PubMed - in process]
2: id: 20202571 Error occurred: The following PMID is not available: 20202571 
3: id: 20202570 Error occurred: The following PMID is not available: 20202570 

4: J Cataract Refract Surg. 2010 Mar;36(3):531-2; author reply 532-4. 

Intraocular lens calculation in extreme myopia.

Preussner PR.

Publication Types:
    Comment
    Letter

PMID: 20202569  [PubMed - in process]

5: J Cataract Refract Surg. 2010 Mar;36(3):530; author reply 530-1. 

Variation of cross-chop technique.

Chee SP.

Publication Types:
    Comment
    Letter

PMID: 20202568  [PubMed - in process]

6: J Cataract Refract Surg. 2010 Mar;36(3):530. 

Benefits of stromal hydration.

Vasavada AR, Mamidipudi PR, Gajjar D, Vasavada V, Vasavada V, Raj S.

Publication Types:
    Comment
    Letter

PMID: 20202567  [PubMed - in process]
7: id: 20202566 Error occurred: The following PMID is not available: 20202566 
8: id: 20202565 Error occurred: The following PMID is not available: 20202565 

9: J Cataract Refract Surg. 2010 Mar;36(3):529; author reply 529. 

Letter to the editor on Calladine et al.

Zafar A.

Publication Types:
    Comment
    Letter

PMID: 20202564  [PubMed - in process]

10: J Cataract Refract Surg. 2010 Mar;36(3):528; author reply 529. 

Factors affecting stromal hydration of clear corneal incision architecture.

Hu YJ, Hou P, Chen WQ.

Publication Types:
    Comment
    Letter

PMID: 20202563  [PubMed - in process]
11: id: 20202562 Error occurred: The following PMID is not available: 20202562 
12: id: 20202561 Error occurred: The following PMID is not available: 20202561 

13: J Cataract Refract Surg. 2010 Mar;36(3):524-7. 

Consultation section. Refractive surgical problem.

[No authors listed]

PMID: 20202560  [PubMed - in process]

14: J Cataract Refract Surg. 2010 Mar;36(3):523. 

Epi-Shugarcaine with plain balanced salt solution for prophylaxis of
intraoperative floppy-iris syndrome.

Schulze R Jr.

Publication Types:
    Letter

PMID: 20202559  [PubMed - in process]

15: J Cataract Refract Surg. 2010 Mar;36(3):522-3. 

Partial retraction of Malyugin pupil expansion device to improve safety during
ring removal.

Rauen M, Oetting T.

Publication Types:
    Letter

PMID: 20202558  [PubMed - in process]

16: J Cataract Refract Surg. 2010 Mar;36(3):521-2. 

Efficacy of topical anesthesia for foldable phakic intraocular lens implantation
for the correction of myopia.

van Philips LA.

Publication Types:
    Letter

PMID: 20202557  [PubMed - in process]

17: J Cataract Refract Surg. 2010 Mar;36(3):517-20. 

Pseudomonas keratitis after collagen crosslinking for keratoconus: case report
and review of literature.

Sharma N, Maharana P, Singh G, Titiyal JS.

Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical
Sciences, New Delhi 110029, India. namrata103@hotmail.com

A 19-year-old woman presented with a 3-day history of pain, redness, and
diminution of vision occurring one day after collagen crosslinking (CXL) with
riboflavin and ultraviolet-A had been performed for keratoconus in the right
eye. On presentation, severe keratitis with a 7.0mm x 6.0mm central infiltrate
was present. Culture results from the patient's contact lens and corneal
scrapings were positive for Pseudomonas aeruginosa. Keratitis can occur
following CXL because of the presence of an epithelial defect, use of a soft
bandage contact lens, and topical corticosteroids in the immediate postoperative
period, and patients should be counseled about it. Copyright  2010 ASCRS and
ESCRS. Published by Elsevier Inc. All rights reserved.

PMID: 20202556  [PubMed - in process]

18: J Cataract Refract Surg. 2010 Mar;36(3):512-6. 

Long-term pathological follow-up of obsolete design: Pannu universal intraocular
lens.

Davis D, Werner L, Strenk S, Strenk L, Yeh O, Mamalis N.

John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA.

We studied an enucleated postmortem eye from an 82-year-old white donor who had
been implanted with a Pannu "universal" intraocular lens (IOL) in the anterior
chamber approximately 20 years earlier. This IOL has design features
characteristic of a 1-piece, C-loop posterior chamber IOL. Magnetic resonance
imaging showed a relatively well-centered IOL in the anterior chamber with
haptics impinging on the iris. Gross and light microscopic analyses of the eye
and the IOL showed peripheral anterior synechiae enclaving one haptic, areas of
angle widening, significant attenuation of the corneal endothelium, multiple
areas of iris trauma secondary to optic and haptic iris abrasion, large areas of
pigment dispersion in the angle, diffuse pigment accumulation within the
anterior chamber, and attenuation of the ganglion cell layer. The
histopathological findings were consistent with glaucoma and chronic
inflammation. Copyright  2010. Published by Elsevier Inc.

Publication Types:
    Research Support, N.I.H., Extramural
    Research Support, Non-U.S. Gov't

PMID: 20202555  [PubMed - in process]

19: J Cataract Refract Surg. 2010 Mar;36(3):508-11. 

Bilateral Descemet membrane detachment after canaloplasty.

Palmiero PM, Aktas Z, Lee O, Tello C, Sbeity Z.

New York Eye and Ear Infirmary, New York, New York 10003, USA.

We report a case of bilateral Descemet membrane detachment (DMD) after
canaloplasty in a 70-year-old Portuguese man with primary open-angle glaucoma.
The patient developed bilateral DMD immediately following consecutive (1 week
apart) canaloplasty surgery in both eyes. Slitlamp biomicroscopy, gonioscopy,
and Fourier-domain optical coherence tomography (FD-OCT) findings are described.
On postoperative day 1, in both cases, slitlamp biomicroscopy revealed an
unscrolled inferonasal DMD and a clear cornea with deep and quiet anterior
chambers. Gonioscopy showed an intact, lightly pigmented, and distended
trabecular meshwork with no evidence of suture extrusion. High-resolution FD-OCT
revealed a widely dilated canal of Schlemm, trabecular distention, and a
retrocorneal hyperreflective membrane corresponding to a DMD. At 3 months, the
DMD resolved spontaneously in both eyes. Although DMD is a known complication of
canaloplasty, the occurrence of bilateral symmetrically located DMDs in our case
suggests a possible anatomical predisposition in addition to factors induced by
the surgical technique. Copyright 2010 ASCRS and ESCRS. Published by Elsevier
Inc. All rights reserved.

PMID: 20202554  [PubMed - in process]

20: J Cataract Refract Surg. 2010 Mar;36(3):503-7. 

Immunohistochemical observation of anterior subcapsular cataract in eye with
spontaneously regressed retinoblastoma.

Shirai K, Okada Y, Saika S.

Department of Ophthalmology, Wakayama Medical University, 811-1 Kimiidera,
Wakayama, 641-0012, Japan. shirai@wakayama-med.ac.jp

We report the histological findings of secondary cataract in an eye with a
spontaneously regressed retinoblastoma to obtain keys to clarify the mechanism
of this phenomenon. During phacoemulsification, opacified anterior capsule was
obtained, fixed in formalin, and embedded in paraffin. Paraffin sections of the
specimen were histologically observed. Hematoxylin-eosin staining showed
extracellular matrix accumulation in the extracted fibrous anterior subcapsular
opacification. Immunohistochemistry revealed the presence of fibrous collagen
types and cellular fibronectin. Presumed lens cells amid matrix were positively
labeled for vimentin, alpha-smooth muscle actin, and phospho-Smad2. Histology of
the fibrous anterior subcapsular opacification tissue showed the possibility of
epithelial-mesenchymal transition of the lens epithelial cells in the secondary
cataract following a spontaneously regressed retinoblastoma. Copyright  2010
ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

PMID: 20202553  [PubMed - in process]

21: J Cataract Refract Surg. 2010 Mar;36(3):497-502. 

Pseudophakic eye with obliquely crossed piggyback toric intraocular lenses.

Jin H, Limberger IJ, Borkenstein AF, Ehmer A, Guo H, Auffarth GU.

Guangdong Eye Institute, Guangdong Academy of Medical Sciences, Guangzhou,
China.

A 72-year-old man presented with high astigmatism (2.25 -5.0 x 45) induced by
long-term rotation of a toric intraocular lens (IOL). Corneal astigmatism was
3.78 diopters (D). The corrected distance visual acuity (CDVA) was 20/32.
Because of the risk of repositioning, a secondary toric IOL of -3.0/6.0 D
especially designed for sulcus implantation was piggybacked through 3.5 mm
sutureless clear-corneal incision with a cylindrical axis obliquely crossed with
that of the primary IOL. Eight months postoperatively, the corneal astigmatism
was 5.04 D. The CDVA was 20/25 with a refraction of 1.0 -2.5 x 70. No
interlenticular opacification or significant rotation or decentration of the
secondary toric IOL was observed. The refractive properties of this pseudophakic
eye were analyzed using a mathematical approach. The calculated postoperative
refraction was 0.84 -1.7 x 47. A piggyback toric IOL can be implanted in an
obliquely crossed style that allows a secondary toric IOL to correct astigmatism
induced by long-term toric IOL rotation. Copyright  2010 ASCRS and ESCRS.
Published by Elsevier Inc. All rights reserved.

Publication Types:
    Research Support, Non-U.S. Gov't

PMID: 20202552  [PubMed - in process]

22: J Cataract Refract Surg. 2010 Mar;36(3):493-6. 

Effect of varying microkeratome parameters on laser in situ keratomileusis
interface surfaces.

Sanka RK, Loft ES, Randleman JB.

Emory Eye Center & Emory Vision, Atlanta, Georgia, USA.

PURPOSE: To evaluate the effect of altering microkeratome parameters
(oscillation rates and head-advance speeds) and repeated blade use on human and
porcine laser in situ keratomileusis interface surface quality and to evaluate
correlations between human and porcine interface surface quality. SETTING: Emory
Vision, Atlanta, Georgia, USA. METHODS: Corneal flaps were created in porcine
eyes and human cadaver eyes with an Amadeus I microkeratome using varying
head-advance speeds and oscillation rates. Microkeratome blades were used once
in 18 porcine eyes, twice in 18 human eyes (simulating clinical use), and 5
times in 15 porcine eyes. The interface surface was imaged with electron
microscopy, with overall bed quality and surface smoothness graded from 1 to 5
(smoothest to roughest) by 5 masked corneal specialists using the same grading
criteria for porcine eyes and human eyes. RESULTS: Neither oscillation rates nor
head-advance speeds consistently influenced bed smoothness in any group. There
were no differences in bed quality between first cuts and second cuts in human
eyes or between porcine eyes with multiple blade use. Porcine eyes had
statistically significantly smoother stromal beds than human eyes (P<.01); there
was no correlation between porcine eye scores and human eye scores (r = -0.1).
CONCLUSIONS: Neither alterations in microkeratome parameters nor repeated blade
use consistently influenced stromal bed quality in human or porcine eyes. No
subjective correlation existed between stromal bed qualities of porcine corneas
and human corneas; therefore, future studies evaluating corneal stromal bed
quality should be performed in human corneas only. Copyright  2010 ASCRS and
ESCRS. Published by Elsevier Inc. All rights reserved.

Publication Types:
    Research Support, N.I.H., Extramural
    Research Support, Non-U.S. Gov't

PMID: 20202551  [PubMed - in process]

23: J Cataract Refract Surg. 2010 Mar;36(3):488-92. 

Ocular penetration of topically applied linezolid in a rabbit model.

Saleh M, Jehl F, Dory A, Lefevre S, Prevost G, Gaucher D, Sauer A, Speeg-Schatz
C, Bourcier T.

Department of Microbiology, Laboratory of Antibiology, University Hospital of
Strasbourg, 1 Place de l'Hopital, 67000 Strasbourg, France.
maher.saleh@chru-strasbourg.fr

PURPOSE: To evaluate ocular penetration of topically applied linezolid, a new
antibiotic agent targeted against gram-positive organisms. SETTING: Laboratory
of Pharmacology, University Hospital of Strasbourg, Strasbourg, France. METHODS:
New Zealand White rabbits were divided into 3 equal groups. One drop of 50
microL (2 mg/mL) linezolid was administrated in Group 1. In Group 2, eyes were
dosed in accordance with a keratitis protocol (1 drop of 2 mg/mL every 15
minutes for 1 hour). Aqueous humor was sampled 6 times from immediately after to
3 hours after drop delivery. In Group 3, a keratitis protocol was implemented
before the animals were humanely killed. Conjunctiva, cornea, vitreous, and
blood samples were collected 1 hour and 2 hours after the last drop. Linezolid
concentrations were measured by high-performance liquid chromatography. RESULTS:
Each group comprised 8 rabbits. In Group 1 and Group 2, the peak linezolid
concentration in the aqueous humor (mean 0.87 mg/L +/- 0.16 [SD] and 2.17 +/-
0.4 mg/L, respectively) was 45 minutes after the last drop delivery. In Group 3,
the concentrations 1 hour and 2 hours after the last drop were higher than 3
microg/g in the conjunctiva samples and higher than 4 microg/g in the cornea
samples. The linezolid concentration in the vitreous and serum was negligible.
CONCLUSIONS: Linezolid levels in the aqueous humor, conjunctiva, and cornea
exceeded the minimum inhibitory concentration of most gram-positive organisms
that cause bacterial keratitis and endophthalmitis. Linezolid could be a
valuable alternative in cases of increased resistance to vancomycin. Copyright
2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

PMID: 20202550  [PubMed - in process]

24: J Cataract Refract Surg. 2010 Mar;36(3):483-7. 

Acrylic intraocular lens damage after folding using a forceps insertion
technique.

Erie JC, Newman B, Mahr MA, Khan AR, McIntosh M.

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA.
erie.jay@mayo.edu

PURPOSE: To analyze intraocular lens (IOL) surface abnormalities seen after
folding using a forceps insertion technique. SETTING: Mayo Clinic, Rochester,
Minnesota, USA. METHODS: Acrylic AcrySof MA60AC IOLs were examined using an Axio
Imager microscope before and after they were folded using a forceps insertion
technique. Differential interference contrast, brightfield reflected light, and
darkfield reflected light imaging techniques were used as necessary. The effects
of temperature, time, and ophthalmic viscosurgical device (OVD) on optic surface
abnormalities after folding were studied. RESULTS: All 17 IOLs examined had
smooth, defect-free optic surfaces before folding. After folding, anterior optic
surface depressions were observed in all IOLs; the depressions corresponded to
the contact area of the titanium insertion forceps. Surface depressions were
present up to 72 hours after folding, were more pronounced when an insertion
forceps with a high degree of wear was used, and were greater when the IOL was
warmed to 98 degrees F before folding. Coating the IOL surface with OVD before
grasping it with the insertion forceps prevented formation of depressions.
CONCLUSIONS: The anterior optic surface of the acrylic IOL was vulnerable to
forceps-induced surface depressions. Surface abnormalities were prevented by
coating the anterior optic surface with OVD before grasping it with a metal
insertion forceps. Copyright  2010 ASCRS and ESCRS. Published by Elsevier Inc.
All rights reserved.

Publication Types:
    Research Support, Non-U.S. Gov't

PMID: 20202549  [PubMed - in process]

25: J Cataract Refract Surg. 2010 Mar;36(3):477-82. 

Comparison of real-time intraocular pressure during laser in situ keratomileusis
and epithelial laser in situ keratomileusis in porcine eyes.

Hernandez-Verdejo JL, de Benito-Llopis L, Teus MA.

Vissum Madrid, Santa Hortensia 58, 28002 Madrid, Spain. jlhernandez@cnoo.es

PURPOSE: To compare real-time intraocular pressure (IOP) between laser in situ
keratomileusis (LASIK) and epithelial LASIK (epi-LASIK) in porcine eyes during
flap creation using a microkeratome or an epikeratome, respectively. SETTING:
Vissum Madrid, Madrid, Spain. METHODS: In this prospective study, a Moria
microkeratome was used in 1 eye (LASIK group) and an Epi-K epikeratome in the
other eye (epi-LASIK group) to create a lamellar corneal flap and an epithelial
flap, respectively, in freshly enucleated porcine eyes. The IOP changes during
the procedures were recorded by direct cannulation using a reusable blood
pressure transducer connected to the anterior chamber. RESULTS: Each group
comprised 17 eyes. In the LASIK group, the mean IOP was 113.65 mm Hg +/- 10.78
(SD) during suctioning and 112.35 +/- 11.51 mm Hg during cutting phases. The
mean duration of the phases was 9.00 +/- 1.46 seconds and 6.06 +/- 1.14 seconds,
respectively. In the epi-LASIK group, the mean IOP was 92.57 +/- 20.86 mm Hg
during suctioning, 82.09 +/- 20 mm Hg during cutting, and 67.28 +/- 13.49 during
low vacuum. The mean duration of the phases was 25.88 +/- 1.96 seconds, 33.82
+/- 2.81 seconds, and 29.71 +/- 3.29 seconds, respectively. The IOP values were
significantly different between the 2 groups (all comparisons P<.05).
CONCLUSION: Real-time IOP measured during suctioning and flap creation by direct
cannulation of the anterior chamber in freshly enucleated porcine eyes showed a
significant increase in IOP during LASIK and epi-LASIK; the increase was lower
in the epi-LASIK group. Copyright  2010 ASCRS and ESCRS. Published by Elsevier
Inc. All rights reserved.

PMID: 20202548  [PubMed - in process]

26: J Cataract Refract Surg. 2010 Mar;36(3):472-6. 

Keratorefractive effect of microwave keratoplasty on human corneas.

Barsam A, Patmore A, Muller D, Marshall J.

Department of Academic Ophthalmology, The Rayne Institute, St. Thomas' Hospital,
London, United Kingdom. abarsam@hotmail.com

PURPOSE: To determine the change in dioptric power on excised human
corneoscleral buttons after microwave keratoplasty application and to determine
the qualitative effect on the cornea using histology and scanning electron
microscopy. SETTING: Department of Academic Ophthalmology, Rayne Institute, St.
Thomas' Hospital, London, United Kingdom. METHODS: Excised human corneoscleral
buttons were treated with a prototype microwave keratoplasty ring applicator. A
28.12 W, 1-second application was performed on the corneas using a 6.0 mm
diameter inner conductor and an 8.4 mm diameter outer conductor.
Videokeratography was performed with a topographic modeling system (TMS-1)
before and after microwave keratoplasty. The induced change in corneal curvature
was calculated using the mean dioptric power of rings situated 2.0 to 6.0 mm
from the geometrical apex of the corneas. Scanning electron microscopy and
toluidine-blue light microscopy were performed to determine the effect on the
corneal stroma. RESULTS: Six excised corneoscleral buttons from 6 donors were
used. The mean reduction in curvature after microwave keratoplasty application
was 3.07 diopters +/- 2.62 (SD). Scanning and light microscopy showed
microwave-induced shrinkage of corneal stromal collagen with little disturbance
to the overlying epithelium. CONCLUSION: Microwave keratoplasty reduced corneal
curvature and has therapeutic potential as a noninvasive alternative to excimer
laser surgical correction of myopia and as a treatment for corneal ectasia.
Copyright  2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

Publication Types:
    Research Support, Non-U.S. Gov't

PMID: 20202547  [PubMed - in process]

27: J Cataract Refract Surg. 2010 Mar;36(3):465-71. 

Straylight measurements in laser in situ keratomileusis and laser-assisted
subepithelial keratectomy for myopia.

Lapid-Gortzak R, van der Linden JW, van der Meulen I, Nieuwendaal C, van den
Berg T.

private refractive surgery clinic, Driebergen, The Netherlands.
r.lapid@amc.uva.nl

PURPOSE: To compare straylight values before and 3 months after laser in situ
keratomileusis (LASIK) and laser-assisted subepithelial keratectomy (LASEK) and
to analyze the causes of any change. SETTING: Private refractive surgery clinic,
Driebergen, The Netherlands. METHODS: Straylight was measured before and after
LASIK or LASEK with a C-Quant straylight meter; values were recorded as the
straylight parameter log(s). Main outcome measures were the difference between
postoperative and preoperative straylight values and factors causing a
difference between the values. RESULTS: The study evaluated 102 eyes having
LASIK and 137 eyes having LASEK. On average, there was significant improvement
in straylight values postoperatively in both groups. The mean decrease was
-0.016 log(s) in the LASIK group and -0.026 log(s) in the LASEK group.
Nonparametric testing (sign test) showed that the improvement in straylight was
statistically significant in more than 50% of eyes in both groups. Straylight
improved in 62 eyes in the LASIK group (P<.001) and 78 eyes in the LASEK group
(P<.02) and deteriorated in 35 eyes and 58 eyes, respectively. There was an
increase in straylight in 17 eyes (7.1%). Clinical correlations were found in
some eyes that had increased postoperative straylight values. CONCLUSION: On
average, straylight values 3 months after LASIK and LASEK were slightly
decreased from baseline values. Copyright  2010 ASCRS and ESCRS. Published by
Elsevier Inc. All rights reserved.

Publication Types:
    Research Support, Non-U.S. Gov't

PMID: 20202546  [PubMed - in process]

28: J Cataract Refract Surg. 2010 Mar;36(3):456-64. 

Limbal relaxing incisions at the time of apodized diffractive multifocal
intraocular lens implantation to reduce astigmatism with or without subsequent
laser in situ keratomileusis.

Muftuoglu O, Dao L, Cavanagh HD, McCulley JP, Bowman RW.

University of Texas Southwestern Medical Center, Department of Ophthalmology,
Dallas, Texas 75390-9057, USA.

PURPOSE: To evaluate the visual and refractive outcomes of limbal relaxing
incisions (LRIs) to reduce astigmatism at the time of apodized diffractive
multifocal intraocular lens (IOL) implantation. SETTING: University of Texas
Southwestern Medical Center at Dallas, Dallas, Texas, USA. METHODS: This
retrospective review comprised consecutive patients who had LRIs at the time of
lens extraction and AcrySof ReSTOR IOL implantation. A subgroup of patients had
subsequent laser in situ keratomileusis (LASIK) for residual refractive error
correction. RESULTS: The study evaluated 73 eyes (59 patients); 21 eyes (28.7%)
of 59 patients had further LASIK (LRI+LASIK). The mean follow-up was 13.2 months
+/- 6.4 (SD). The mean keratometric astigmatism decreased from 1.49 +/- 0.71
diopters (D) preoperatively to 0.56 +/- 0.57 D at the last follow-up (P<.001).
Although the LRI+LASIK group had significantly greater corneal astigmatism than
the LRI-only group preoperatively (P = .005) and 1 month (P = .030) and 6-months
(P = .014) postoperatively, there was no statistically significant difference
between the 2 groups at the last follow-up (P = .528). At the last follow-up,
the uncorrected distance visual acuity was 20/25 or better and the uncorrected
near visual acuity was J1 or better in 32 (76%) of 42 eyes in the LRI-only group
and in 17 (81%) of 21 eyes in the LRI+LASIK group. CONCLUSION: Limbal relaxing
incisions at the time of apodized diffractive multifocal IOL implantation, with
or without subsequent LASIK, were effective and safe in reducing astigmatism.
Copyright  2010. Published by Elsevier Inc.

Publication Types:
    Research Support, Non-U.S. Gov't

PMID: 20202545  [PubMed - in process]

29: J Cataract Refract Surg. 2010 Mar;36(3):449-55. 

First clinical results of epithelial laser in situ keratomileusis with a 1000 Hz
excimer laser.

Winkler von Mohrenfels C, Khoramnia R, Wullner C, Donitzky C, Salgado J, Pfaffl
W, Lohmann CP.

Augenklinik Klinikum Rechts der Isar, Technische Universitat Munchen,
Ismaningerstrasse 22, 81675 Munich, Germany. christoph.wvm@gmail.com

PURPOSE: To evaluate the safety, stability, and efficacy of the first clinical
cases of epithelial laser in situ keratomileusis (epi-LASIK) performed using a
1000 Hz excimer laser system. SETTING: Klinikum Rechts der Isar, Munich,
Germany. METHODS: The epi-LASIK procedure was performed using an EpiLift
microkeratome and a WaveLight Concept System 1000 laser. Preoperatively and 1,
3, and 6 months postoperatively, a complete ophthalmic examination was
performed. The examination included objective and subjective refraction,
uncorrected and corrected distance visual acuities, and topography. RESULTS: The
study comprised 30 eyes of 17 patients. The mean spherical equivalent was -4.36
diopters (D) +/-1.77 (SD) preoperatively, 0.07 +/- 0.38 D 1 month
postoperatively, -0.06 D +/- 0.25 D at 3 months, and -0.05 +/- 0.24 D at 6
months. Six months postoperatively, 90% of patients were within +/-0.50 D of the
intended correction and all were within +/-1.00 D. At 3 months, 25 eyes had a
clear cornea and 5 eyes had trace haze. CONCLUSIONS: In this pilot series, the
use of the 1000 Hz excimer laser did not lead to the clinical side effects that
are potentially associated with the use of a high repetition rate. The safety,
stability, and efficacy of the laser were high although no adjustments to the
nomogram were made. Copyright  2010 ASCRS and ESCRS. Published by Elsevier Inc.
All rights reserved.

PMID: 20202544  [PubMed - in process]

30: J Cataract Refract Surg. 2010 Mar;36(3):442-8. 

Efficacy, safety, and flap dimensions of a new femtosecond laser for laser in
situ keratomileusis.

Vryghem JC, Devogelaere T, Stodulka P.

private practice, Boulevard Saint-Michel, 12-16, B-1150 Brussels, Belgium.
info@vryghem.be

PURPOSE: To evaluate the clinical results of a preproduction femtosecond laser
for flap creation in laser in situ keratomileusis (LASIK). SETTING: Private
practice, Brussels, Belgium. METHODS: This study comprised myopic eyes with a
plano target refraction and a target flap thickness of 110 microm. The LASIK
flap was created with a Ziemer LDV femtosecond laser. Prospective evaluation
included flap dimensions, intraoperative and postoperative complications, and
visual outcomes. RESULTS: Sixty-three patients (111 eyes; mean age 37.2 years)
were evaluated. Preoperatively, the mean corrected distance visual acuity (CDVA)
was 1.34 (Snellen) and the mean manifest refraction spherical equivalent (MRSE),
-4.91 diopters (D) +/- 2.45 (SD). Six months postoperatively, the mean CDVA was
1.33; the mean MRSE, -0.05 +/- 0.3 D; and the mean uncorrected distance visual
acuity (UDVA), 1.27. The UDVA was 20/25 or better in 98.2% of eyes and 20/20 or
better in 94.6% of eyes. The MRSE was within +/-0.50 D in 95.5% of eyes and
within +/-1.00 D in 99.1% of eyes. The cylinder was 0.50 D or less in 99.1% of
eyes. The mean flap thickness was 106.6 +/- 12.6 microm. The most frequent
complications were epithelial sloughing (10.8%), a decentered cut (4.5%), flap
adhesions (5.4%), a slightly irregular flap border (5.4%), and microstriae
(5.4%); all were mild. CONCLUSIONS: Overall, the flap dimensions and refractive
results were predictable and the complication rate was acceptable after LASIK
using the new femtosecond laser for flap creation. Copyright 2010 ASCRS and
ESCRS. Published by Elsevier Inc. All rights reserved.

PMID: 20202543  [PubMed - in process]