Journal Contents

Am Jour Ophthalmol
Br J Ophthalmol
Can J Ophthalmol
J Cat Ref Surg
Curr Eye Res
Eur J Ophthalmol
J Glaucoma
JAMA Ophthalmol
Graefes Ophthalmol
Indian J Ophthalmol
Int Ophthalmol Clin
Invest Ophth Vis Sci
Jpn J Ophthalmol
Korean J Ophthal
J Neuroophthalmol
Ophthalmic Epidemiol
Ophthalmic Genet
Ophthal Plast Rec Surg
Ophthalmic Res
Surv Ophthalmol
Ophthalmology Review Journal
Eye[JOUR] Established 1995
1. Eye (Lond). 2014 Dec;28(12):1528. doi: 10.1038/eye.2014.257.

A subtle case of hydroxychloroquine retinopathy: spectral domain optical
coherence tomography findings.

Barnes AC, Bhavsar KV, Weber ML, Witkin AJ.

PMID: 25503058   [PubMed - in process]

2. Eye (Lond). 2014 Dec;28(12):1527. doi: 10.1038/eye.2014.259.

Variations in the cone packing density with eccentricity in emmetropes.

Dabir S, Mangalesh S, Kumar KA, Kummelil MK, Sinha Roy A, Shetty R.

PMID: 25503057   [PubMed - in process]

3. Eye (Lond). 2014 Dec;28(12):1395-8. doi: 10.1038/eye.2014.266.

Annual acknowledgement of manuscript reviewers.

[No authors listed]

PMID: 25503056   [PubMed - in process]

4. Eye (Lond). 2014 Dec 12. doi: 10.1038/eye.2014.299. [Epub ahead of print]

Choroid thickness and ocular pulse amplitude in migraine during attack.

Dervisogullari MS(1), Totan Y(1), Gençler OS(1).

Author information: 
(1)Department of Ophthalmology, Turgut Ozal University, Ankara, Turkey.

AimTo compare the choroidal thickness and ocular pulse amplitude (OPA)
measurements obtained during the attack period in migraine patients and age and
gender matched control group participants using high definition optical coherence
tomography (OCT).MethodsThirty eyes at the side of the headache of 30 subjects
with a diagnosis of migraine with or without aura and unilateral migraine and 29 
age and gender matched healthy participants were enrolled in this observational, 
cross-sectional study. OCT scans were performed to all participants. Choroidal
thicknesses were measured at the fovea, 1500 μm nasal and 1500 μm temporal to the
fovea. Intraocular pressure (IOP) and OPA were also measured.ResultsThe choroidal
thickness measurements obtained during the attack period in migraine patients
were (mean±SD) 279.82±35.87, 250.05±29.49, and 239.58±27.92 and in control group 
were 308.20±44.97, 276.95±41.39, and 281.60±41.38 at foveal, nasal, and temporal 
measurement points, respectively. Choroidal thickness significantly decreased
according to the control group (P<0.05) at all measured points in migraine
patients during attack. IOP (mean±SD) values were 16.71±3.26 and17.40±3.19 and
OPA (mean±SD) values were 2.26±0.81 and 2.64±1.03 in migraine and control groups,
respectively, and did not seem to be changed (P>0.05).ConclusionsChoroidal
thickness was found to be significantly decreased in unilateral migraine patients
during the attack period when compared with the control group, whereas OPA did
not change. The possible implications of these findings on the association
between migraine and glaucoma are discussed.Eye advance online publication, 12
December 2014; doi:10.1038/eye.2014.299.

PMID: 25502868   [PubMed - as supplied by publisher]

5. Eye (Lond). 2014 Dec 12. doi: 10.1038/eye.2014.294. [Epub ahead of print]

Surgical outcome of safe surgery system trabeculectomy combined with cataract

Khandelwal RR(1), Raje D(2), Rathi A(1), Agashe A(1), Majumdar M(1), Khandelwal

Author information: 
(1)Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata 
Mangeshkar Hospital, Nagpur, India. (2)MDS Bioanalytics, Nagpur, India.

PurposeTo determine the efficacy of safe surgery system trabeculectomy combined
with manual small incision cataract surgery/phacoemulsification in primary
glaucoma coexistent with cataract.MethodsThis is a retrospective analysis of 105 
cases who underwent single-site combined surgery between January 2008 and
December 2009. Safe surgery system trabeculectomy with diffuse and posterior
application of mitomycin C was performed in all cases. Cataract extraction was
done either by Manual Small Incision Cataract Surgery (MSICS) or
phacoemulsification. Main outcome measures were success rate of trabeculectomy,
as determined by four different IOP goals and incidence of postoperative
complications. Analysis was performed using R-2.15, and the significance was
tested at 5% level.ResultsThe minimum follow-up period was 12 months. The overall
success rates (with or without medication) when safe surgery system
trabeculectomy was combined with MSICS were 91, 70, and 51% for IOP ≤18, ≤15, and
≤12 mm Hg, respectively, and target IOP was achieved in 72% cases. The mean IOP
reduction was 43.8% with MSICS and 42.08% with phacoemulsification. The surgical 
outcome was not significantly different for both techniques. Postoperative
complications were infrequent and comparable.ConclusionThe Safe Surgery System
Trabeculectomy combined with cataract surgery offers excellent IOP control with
minimal postoperative complications. It offers an effective and improved solution
for primary glaucoma coexistent with cataract found in developing countries.Eye
advance online publication, 12 December 2014; doi:10.1038/eye.2014.294.

PMID: 25502867   [PubMed - as supplied by publisher]

6. Eye (Lond). 2014 Dec 12. doi: 10.1038/eye.2014.288. [Epub ahead of print]

The fate of ophthalmology trainees in the UK-CCT Holders 2007 to 2010.

Bowes O(1), Pradeep A(1), Lim LT(1), Grant S(1), Dean WH(1), O'Gallagher M(1),
Idrees F(1), Hanspal I(1), Niyadurupola N(1); Ophthalmic Trainees’ Group;
Ophthalmic Trainees' Group.

Collaborators: Dean W, Connor A, Bladen J, Bowes O, Chawla A, Dowlut S, Ghauri
AJ, Johnson M, Lewis K, Lim LT, Mookhtiar M, Pradeep A, Saldanha M, Symes R.

Author information: 
(1)Ophthalmic Trainees' Group, Royal College of Ophthalmologists, London, UK.

PMID: 25502866   [PubMed - as supplied by publisher]

7. Eye (Lond). 2014 Dec 5. doi: 10.1038/eye.2014.284. [Epub ahead of print]

The cortex is in overall control of 'voluntary' eye movement.

Pouget P(1).

Author information: 
(1)1] CNRS 7225, Paris, France [2] ICM, Paris, France [3] Université Pierre et
Marie Curie, Paris, France.

The neural circuits that control eye movements are complex and distributed in
brainstem, basal ganglia, cerebellum, and multiple areas of cortex. The
anatomical function of the substrates implicated in eye movements has been
studied for decades in numerous countries, laboratories, and clinics. The modest 
goal of this brief review is twofold. (1) To present a focused overview of the
knowledge about the role of the cerebral cortex in voluntary control of eye
movements. (2) To very briefly mention two findings showing that the accepted
hierarchy between the frontal and the occipital sensory areas involved in
sensory-motor transformation might not be so trivial to reconcile, and to
interpret in the context of eye movement command. This presentation has been part
of the 44th Cambridge Ophthalmological Symposium, on ocular motility, 3 September
2014 to 5 November 2014.Eye advance online publication, 5 December 2014;

PMID: 25475239   [PubMed - as supplied by publisher]

8. Eye (Lond). 2014 Dec 5. doi: 10.1038/eye.2014.287. [Epub ahead of print]

Intraocular xanthomatous tumor presenting as fulminant uveitis.

Cheng CY(1), Chen PY(2), Lin CJ(3).

Author information: 
(1)Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan.
(2)Department of Pathology, Changhua Christian Hospital, Changhua, Taiwan. (3)1] 
Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan [2]
Department of Ophthalmology, China Medical University Hospital, Taichung, Taiwan 
[3] School of Medicine, China Medical University, Taichung, Taiwan.

PMID: 25475238   [PubMed - as supplied by publisher]

9. Eye (Lond). 2014 Dec 5. doi: 10.1038/eye.2014.285. [Epub ahead of print]

Intrastromal corneal rings and corneal collagen crosslinking for progressive
keratoconus: comparison of two sequences.

Saib N(1), Bonnel S(1), Fenolland JR(1), Abrieu M(1), Rambaud C(1), Berguiga
M(1), Froussart-Maille F(1), Rigal-Sastourne JC(1).

Author information: 
(1)Department of Ophthalmology, Hôpital d'instruction des armées de Percy,
Clamart, France.

PMID: 25475237   [PubMed - as supplied by publisher]

10. Eye (Lond). 2014 Dec 5. doi: 10.1038/eye.2014.286. [Epub ahead of print]

Efficacy and safety of patching vs bandage lens on postoperative pain following
pterygium surgery.

Yeung SN(1), Lichtinger A(2), Kim P(2), Elbaz U(2), Ku JY(2), Teichman JC(3),
Amiran MD(2), Slomovic AR(2).

Author information: 
(1)1] Department of Ophthalmology, Toronto Western Hospital, University Health
Network, Toronto, ON, Canada [2] Department of Ophthalmology, University of
British Columbia, Vancouver, BC, Canada. (2)Department of Ophthalmology, Toronto 
Western Hospital, University Health Network, Toronto, ON, Canada. (3)Department
of Ophthalmology, McMaster University, Hamilton, ON, Canada.

PMID: 25475236   [PubMed - as supplied by publisher]

11. Eye (Lond). 2014 Dec 5. doi: 10.1038/eye.2014.289. [Epub ahead of print]

Alport syndrome with phenotypic marfanoid habitus: atypical case series.

Agrawal N(1), Nayak DP(1), Gupta P(1), Haripriya A(1), Bhuwania P(1).

Author information: 
(1)Aravind Eye Hospital, Madurai, India.

PMID: 25475235   [PubMed - as supplied by publisher]

12. Eye (Lond). 2014 Dec 5. doi: 10.1038/eye.2014.279. [Epub ahead of print]

Stereo vision and strabismus.

Read JC(1).

Author information: 
(1)Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.

Binocular stereopsis, or stereo vision, is the ability to derive information
about how far away objects are, based solely on the relative positions of the
object in the two eyes. It depends on both sensory and motor abilities. In this
review, I briefly outline some of the neuronal mechanisms supporting stereo
vision, and discuss how these are disrupted in strabismus. I explain, in some
detail, current methods of assessing stereo vision and their pros and cons.
Finally, I review the evidence supporting the clinical importance of such
measurements.Eye advance online publication, 5 December 2014;

PMID: 25475234   [PubMed - as supplied by publisher]

13. Eye (Lond). 2014 Dec 5. doi: 10.1038/eye.2014.283. [Epub ahead of print]

We need to pay heed to the psychosocial aspects of strabismus.

Marsh IB(1).

Author information: 
(1)Ophthalmology Department, University Hospital Aintree, Liverpool, UK.

Adult strabismus surgery has long been regarded as cosmetic. This paper
summarises the current evidence that this statement should be discarded. The
evidence shows that strabismus surgery in non-diplopic adult patients can be
beneficial in both functional and psychological situations. It is suggested that 
the term cosmetic would be better replaced by reconstructive.Eye advance online
publication, 5 December 2014; doi:10.1038/eye.2014.283.

PMID: 25475233   [PubMed - as supplied by publisher]

14. Eye (Lond). 2014 Nov 28. doi: 10.1038/eye.2014.281. [Epub ahead of print]

Review: minimally invasive strabismus surgery.

Mojon DS(1).

Author information: 
(1)1] University of Bern, Bern, Switzerland [2] Department of Ophthalmology,
Allgemeines Krankenhaus, Linz, Austria [3] Airport Medical Center Eye Clinic,
Zürich, Switzerland.

This article reviews the principles and different techniques used to perform
minimally invasive strabismus surgery (MISS). This term is used for strabismus
surgeries minimizing tissue disruption. Muscles are not accessed through one
large opening, but using several keyhole openings placed where needed for the
surgical steps. If necessary, tunnels are created between cuts, which will allow 
performing additional surgical steps. To keep the keyhole openings small,
transconjunctival suturing techniques are used. The cuts are always placed as far
away from the limbus as feasible. This will reduce the risk for postoperative
corneal complications and it will ensure that all cuts will be covered by the
eyelids, minimizing postoperative visibility of surgery and patient discomfort.
Benefits from minimizing anatomical disruption between the muscle and the
surrounding tissue are a better preservation of muscle function, less swelling,
and pain, and more ease to perform reoperations. MISS openings allow to perform
all types of strabismus surgeries, namely rectus muscle recessions, resections,
plications, reoperations, retroequatorial myopexias, transpositions, oblique
muscle recessions, or plications, and adjustable sutures, even in the presence of
restricted motility.Eye advance online publication, 28 November 2014;

PMID: 25431106   [PubMed - as supplied by publisher]

15. Eye (Lond). 2014 Nov 21. doi: 10.1038/eye.2014.262. [Epub ahead of print]

A brief review of the clinical anatomy of the vestibular-ocular connections-how
much do we know?

Bronstein AM(1), Patel M(1), Arshad Q(1).

Author information: 
(1)Academic Department of Neuro-otology, Charing Cross Hospital Campus, Imperial 
College London, London, UK.

The basic connectivity from the vestibular labyrinth to the eye muscles
(vestibular ocular reflex, VOR) has been elucidated in the past decade, and we
summarise this in graphic format. We also review the concept of 'velocity
storage', a brainstem integrator that prolongs vestibular responses. Finally, we 
present new discoveries of how complex visual stimuli, such as binocular rivalry,
influence VOR processing. In contrast to the basic brainstem circuits, cortical
vestibular circuits are far from being understood, but parietal-vestibular nuclei
projections are likely to be involved.Eye advance online publication, 21 November
2014; doi:10.1038/eye.2014.262.

PMID: 25412719   [PubMed - as supplied by publisher]

16. Eye (Lond). 2014 Nov 21. doi: 10.1038/eye.2014.270. [Epub ahead of print]

Pattern strabismus and torsion needs special surgical attention.

Kekunnaya R(1), Mendonca T(1), Sachdeva V(2).

Author information: 
(1)Jasti V Ramanamma Children's Eye Care Center, L V Prasad Eye Institute, KAR
campus, Hyderabad, India. (2)Nimmagadda Prasad Children's Eye Care Center, L V
Prasad Eye Institute, GMRV Campus, Visakhapatnam, India.

Pattern strabismus is relatively common in strabismus practice. Although it is
classically used to include A and V patterns, the term has been expanded to
include additional vertically incomitant horizontal strabismus. This article
reviews the clinical features, etiopathogenesis, and surgical options for the
patients with pattern strabismus.Eye advance online publication, 21 November
2014; doi:10.1038/eye.2014.270.

PMID: 25412718   [PubMed - as supplied by publisher]

17. Eye (Lond). 2014 Nov 21. doi: 10.1038/eye.2014.249. [Epub ahead of print]

Indemnity for orthoptist-delivered intravitreal injections.

DaCosta J(1), Hamilton R(1), Nago J(1), Mapani A(1), Kennedy E(1), Luckett T(1), 
Pavesio C(1), Flanagan D(1).

Author information: 
(1)Moorfields Eye Hospital, London, UK.

PMID: 25412717   [PubMed - as supplied by publisher]

18. Eye (Lond). 2014 Nov 21. doi: 10.1038/eye.2014.276. [Epub ahead of print]

Ocular motor abnormalities in neurodegenerative disorders.

Antoniades CA(1), Kennard C(1).

Author information: 
(1)Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford

Eye movements are a source of valuable information to both clinicians and
scientists as abnormalities of them frequently act as clues to the localization
of a disease process. Classically, they are divided into two main types: those
that hold the gaze, keeping images steady on the retina (vestibulo-ocular and
optokinetic reflexes) and those that shift gaze and redirect the line of sight to
a new object of interest (saccades, vergence, and smooth pursuit). Here we will
review some of the major ocular motor abnormalities present in neurodegenerative 
disorders.Eye advance online publication, 21 November 2014;

PMID: 25412716   [PubMed - as supplied by publisher]

19. Eye (Lond). 2014 Nov 21. doi: 10.1038/eye.2014.280. [Epub ahead of print]

Retrospective contralateral study comparing Descemet membrane endothelial
keratoplasty with Descemet stripping automated endothelial keratoplasty.

Maier AK(1), Gundlach E(1), Gonnermann J(1), Klamann MK(1), Bertelmann E(1),
Rieck PW(2), Joussen AM(1), Torun N(1).

Author information: 
(1)Department of Ophthalmology, Charité-Universitätsmedizin Berlin, Campus
Virchow Klinikum, Charité, Germany. (2)Eye Clinic am Kapellenberg, Potsdam,

PurposeIn this retrospective study, the visual outcomes and postoperative
complications after Descemet stripping automated endothelial keratoplasty (DSAEK)
and Descemet membrane endothelial keratoplasty (DMEK) in the fellow eye were
compared. The patient's satisfaction was evaluated.MethodsA retrospective
analysis of 10 patients, who underwent DSAEK in one eye and DMEK surgery in their
fellow eye, was performed. Intraoperative and postoperative complications were
recorded. Visual and refractive outcomes were evaluated, including higher-order
aberrations (HOA) and contrast thresholds. A subjective questionnaire was used to
evaluate patient satisfaction.ResultsBest-corrected visual acuity (BCVA) was
significantly better in DMEK when compared with DSAEK (0.16±0.10 vs 0.45±0.58
logMAR, P=0.043). Contrast threshold was significantly higher after DMEK than
after DSAEK (0.49±0.23 vs 0.25±0.18, P=0.043). Post-keratoplasty astigmatism,
mean spherical equivalent, and HOA did not differ. Nine out of ten patients
preferred the DMEK procedure. Visual outcome (4.80±1.14 vs 4.50±1.58, P=0.257),
surgery associated pain and burden (DMEK: 1.30±0.48 vs DSAEK: 1.30±0.48, P=1.0), 
estimated time for recovery and rehabilitation (27.6±54.0 vs 24.9±54.8 days,
P=0.173), and mean patient satisfaction (5.40±0.84 vs 5.00±1.05, P=0.257) were
evaluated equally.ConclusionPatient satisfaction reached high, equal values after
DMEK and after DSAEK. Nevertheless, patients preferred DMEK, if given a choice.
Reasons for the preference may include better uncorrected and BCVA, and
especially a better contrast sensitivity.Eye advance online publication, 21
November 2014; doi:10.1038/eye.2014.280.

PMID: 25412715   [PubMed - as supplied by publisher]

20. Eye (Lond). 2014 Nov 21. doi: 10.1038/eye.2014.234. [Epub ahead of print]

Utilisation of orthoptists to give intravitreal injections-a multidisciplinary

Mall SP(1), North L(2), Menon G(2), Moorman CM(1), Downes SM(1).

Author information: 
(1)Oxford Eye Hospital, Oxford Universities NHS Trust, Oxford, UK. (2)Frimley
Park Hospital NHS Foundation Trust, Surrey, UK.

PMID: 25412714   [PubMed - as supplied by publisher]