Journal Contents

Am Jour Ophthalmol
Br J Ophthalmol
Can J Ophthalmol
J Cat Ref Surg
Cornea
Curr Eye Res
Eur J Ophthalmol
Eye
J Glaucoma
JAMA Ophthalmol
Graefes Ophthalmol
Indian J Ophthalmol
Int Ophthalmol Clin
Invest Ophth Vis Sci
Jpn J Ophthalmol
JPOS
Korean J Ophthal
J Neuroophthalmol
Ophthalmic Epidemiol
Ophthalmic Genet
Ophthal Plast Rec Surg
Ophthalmic Res
Ophthalmologica
Ophthalmology
Retina
Surv Ophthalmol
Ophthalmology Review Journal
Can J Ophthalmol[JOUR] Established 1995
1. Can J Ophthalmol. 2015 Oct;50(5):e97-9. doi: 10.1016/j.jcjo.2015.05.006. Epub
2015 Jul 23.

External ocular infections due to methicillin-resistant Staphylococcus aureus and
medical history.

Sato K(1).

Author information: 
(1)Nikko Memorial Hospital, Muroran, Japan. Electronic address:
vze04311@nifty.ne.jp.

PMID: 26455994   [PubMed - in process]


2. Can J Ophthalmol. 2015 Oct;50(5):e96-7. doi: 10.1016/j.jcjo.2015.07.007.

Enhancement of the optic nerve sheath and temporal arteries from giant cell
arteritis.

Chen JJ(1), Kardon RH(2), Daley TJ(3), Longmuir RA(4).

Author information: 
(1)University of Iowa, Iowa City, Iowa; Mayo Clinic; Department of Veterans
Affairs, Rochester, Minnesota, Iowa City. (2)University of Iowa, Iowa City, Iowa;
Department of Veterans Affairs, Iowa City. (3)Medical Associates, Dubuque, Iowa. 
(4)University of Iowa, Iowa City, Iowa. Electronic address:
reid-longmuir@uiowa.edu.

PMID: 26455993   [PubMed - in process]


3. Can J Ophthalmol. 2015 Oct;50(5):e93-6. doi: 10.1016/j.jcjo.2015.06.008.

Optical coherence tomography angiography (OCT-A) of type 2 retinal arteriovenous 
malformation.

Sharma P(1), Sridhar J(1), Rayess N(1), Maguire JI(2).

Author information: 
(1)Retina Service of Wills Eye Hospital, Midatlantic Retina, Wills Eye Hospital, 
Philadephia, Penn. (2)Retina Service of Wills Eye Hospital, Midatlantic Retina,
Wills Eye Hospital, Philadephia, Penn. Electronic address:
jmaguire@midatlanticretina.com.

PMID: 26455992   [PubMed - in process]


4. Can J Ophthalmol. 2015 Oct;50(5):e91-3. doi: 10.1016/j.jcjo.2015.06.006.

Chorioretinitis with exudative retinal detachment secondary to varicella zoster
virus.

Le TD(1), Weisbrod D(2), Mandelcorn ED(3).

Author information: 
(1)University of Toronto, Toronto, Ont. Electronic address:
tranleleung@gmail.com. (2)University of Toronto, Toronto, Ont; Sunnybrook Health 
Sciences Centre, Toronto, Ont. (3)University of Toronto, Toronto, Ont; Toronto
Western Hospital, University Health Network, Toronto, Ont.

PMID: 26455991   [PubMed - in process]


5. Can J Ophthalmol. 2015 Oct;50(5):e88-91. doi: 10.1016/j.jcjo.2015.05.020.

Sustained and expedited resolution of diabetic papillopathy with combined PRP and
bevacizumab.

Chin EK(1), Almeida DR(2), Sohn EH(2).

Author information: 
(1)University of Iowa, Iowa City, Iowa. Electronic address: chin.eric@gmail.com. 
(2)University of Iowa, Iowa City, Iowa.

PMID: 26455990   [PubMed - in process]


6. Can J Ophthalmol. 2015 Oct;50(5):e85-8. doi: 10.1016/j.jcjo.2015.05.019.

Retinal nerve fibre layer defect associated with MELAS syndrome.

Cho KJ(1), Yu J(2).

Author information: 
(1)Dankook University Medical College, Cheonan, Korea. (2)Dankook University
Medical College, Cheonan, Korea. Electronic address: dryujs@dankook.ac.kr.

PMID: 26455989   [PubMed - in process]


7. Can J Ophthalmol. 2015 Oct;50(5):e82-5. doi: 10.1016/j.jcjo.2015.07.002.

Resolution of siderosis glaucoma from chronic intraocular foreign body without
glaucoma surgery.

Ding J(1), Yoganathan P(2), Fernando-Sieminski S(1).

Author information: 
(1)Ross Eye Institute, University at Buffalo, State University of New York,
Buffalo, N.Y. (2)Ross Eye Institute, University at Buffalo, State University of
New York, Buffalo, N.Y.. Electronic address: deepa_yoganathan@yahoo.com.

PMID: 26455988   [PubMed - in process]


8. Can J Ophthalmol. 2015 Oct;50(5):e78-81. doi: 10.1016/j.jcjo.2015.06.005.

Orbital myeloid sarcoma in adults presenting with exposure keratopathy and
hearing loss.

Rath S(1), Agarwal S(2), Charan Das P(2), Tripathy D(1), Mittal R(3).

Author information: 
(1)Ophthalmic Plastic Surgery, Orbit and Ocular Oncology Services, LV Prasad Eye 
Institute. (2)Hi-Tech Medical College and Hospital. (3)Dalmia Ophthalmic
Pathology Service, LV Prasad Eye Institute, Bhubaneswar, India. Electronic
address: dr.rmittal@gmail.com.

PMID: 26455987   [PubMed - in process]


9. Can J Ophthalmol. 2015 Oct;50(5):e74-8. doi: 10.1016/j.jcjo.2015.05.017.

Retinal vasoproliferative tumour in an adolescent who had medulloblastoma: a case
report.

Marcelo-Tan MC(1), Parsons HM(2).

Author information: 
(1)University of British Columbia, Retina Surgical Associates, New Westminster.
(2)University of British Columbia, Retina Surgical Associates, New Westminster;
Surrey Memorial Hospital, Surrey, B.C., Canada. Electronic address:
hughmparsons@gmail.com.

PMID: 26455986   [PubMed - in process]


10. Can J Ophthalmol. 2015 Oct;50(5):e71-4. doi: 10.1016/j.jcjo.2015.05.016.

Two cases of panuveitis with orbital inflammatory syndrome after influenza
vaccination.

Manusow JS(1), Rai A(1), Yeh S(2), Mandelcorn ED(3).

Author information: 
(1)University of Toronto, Toronto, Ont; University Health Network/Toronto Western
Hospital, Toronto, Ont. (2)Emory University, Emory Eye Center, Atlanta, Ga.
(3)University of Toronto, Toronto, Ont; University Health Network/Toronto Western
Hospital, Toronto, Ont. Electronic address: efrem.mandelcorn@utoronto.ca.

PMID: 26455985   [PubMed - in process]


11. Can J Ophthalmol. 2015 Oct;50(5):e69-71. doi: 10.1016/j.jcjo.2015.04.016.

Papilledema in an otherwise clinically typical case of Miller Fisher syndrome.

Bruce CT(1), McClelland CM(2), Van Stavern GP(2).

Author information: 
(1)Washington University, St. Louis, Mo.. Electronic address:
carl.tbruce@gmail.com. (2)Washington University, St. Louis, Mo.

PMID: 26455984   [PubMed - in process]


12. Can J Ophthalmol. 2015 Oct;50(5):e67-9. doi: 10.1016/j.jcjo.2015.03.014.

Secondary localized corneal amyloidosis caused by lower eyelid epiblepharon.

Choe JY(1), Kim N(2).

Author information: 
(1)Department of Pathology, Seoul National University Bundang Hospital, Seongnam,
Korea. (2)Department of Ophthalmology, Seoul National University Bundang
Hospital, Seongnam, Korea. Electronic address: resourceful@hanmail.net.

PMID: 26455983   [PubMed - in process]


13. Can J Ophthalmol. 2015 Oct;50(5):e66-7. doi: 10.1016/j.jcjo.2015.03.013.

Erlotinib-associated bilateral anterior uveitis: resolution with posterior
sub-Tenon's triamcinolone without erlotinib cessation.

Kirkpatrick CA(1), Almeida DR(2), Hornick AL(2), Chin EK(2), Boldt HC(2).

Author information: 
(1)University of Iowa Hospitals & Clinics, Iowa City, Iowa. Electronic address:
christopher.a.kirkpatrick@gmail.com. (2)University of Iowa Hospitals & Clinics,
Iowa City, Iowa.

PMID: 26455982   [PubMed - in process]


14. Can J Ophthalmol. 2015 Oct;50(5):e65-6. doi: 10.1016/j.jcjo.2015.03.012. Epub
2015 Jul 21.

Primary choroidal vitiligo mimicking multifocal choroiditis.

Botsford B(1), Muakkassa NW(1), Witkin AJ(2).

Author information: 
(1)Tufts Medical Center, Boston, Mass. (2)Tufts Medical Center, Boston, Mass.
Electronic address: ajwitkin@gmail.com.

PMID: 26455981   [PubMed - in process]


15. Can J Ophthalmol. 2015 Oct;50(5):396. doi: 10.1016/j.jcjo.2015.08.001.

Author reply.

Iordanous Y(1), Sheidow TG(2).

Author information: 
(1)Ivey Eye Institute, Department of Ophthalmology, University of Western
Ontario. Electronic address: iordanous@gmail.com. (2)Ivey Eye Institute,
Department of Ophthalmology, University of Western Ontario.

PMID: 26455980   [PubMed - in process]


16. Can J Ophthalmol. 2015 Oct;50(5):395. doi: 10.1016/j.jcjo.2015.06.009.

Intravitreal ranibizumab for treatment of fibrovascular pigment epithelial
detachment in age-related macular degeneration.

Yolcu U(1), Tas A(2), Altun S(3).

Author information: 
(1)Sarıkamış Military Hospital, Kars, Turkey. Electronic address:
umit_yolcu@hotmail.com. (2)Agri Military Hospital, Agri, Turkey. (3)GATA Medical 
School, Ankara, Turkey.

PMID: 26455979   [PubMed - in process]


17. Can J Ophthalmol. 2015 Oct;50(5):395-6. doi: 10.1016/j.jcjo.2015.04.015.

Ethical considerations in adoption of femtosecond laser-assisted cataract surgery
by Canadian ophthalmologists.

McAlister C(1).

Author information: 
(1)University of Toronto, Toronto, Ont.. Electronic address:
chryssa.mcalister@gmail.com.

PMID: 26455978   [PubMed - in process]


18. Can J Ophthalmol. 2015 Oct;50(5):393-4. doi: 10.1016/j.jcjo.2015.04.017.

Experience of New Brunswick ophthalmologists using intravitreal anti-vascular
endothelial growth factor.

Giberson M(1), Taylor V(2).

Author information: 
(1)Dalhousie Medicine New Brunswick, Saint John. Electronic address:
mariah.giberson@dal.ca. (2)Department of Ophthalmology & Visual Sciences,
Dalhousie University, Moncton, N.B.

PMID: 26455977   [PubMed - in process]


19. Can J Ophthalmol. 2015 Oct;50(5):388-92. doi: 10.1016/j.jcjo.2015.05.018.

A survey for the need of translational aids among Canadian ophthalmologists.

Mednick ZD(1), Cao K(2), Braga-Mele R(2).

Author information: 
(1)Department of Ophthalmology, Queen's University. (2)Department of
Ophthalmology, University of Toronto; Kensington Eye Institute, Toronto, Ont.

OBJECTIVE: To conduct a needs assessment survey of Canadian ophthalmologists to
determine whether there is a requirement for translational aids in ophthalmology,
and if so, the content, format, and languages to include.
DESIGN: Anonymous voluntary online needs assessment questionnaire.
PARTICIPANTS: A total of 139 ophthalmologists completed the online needs
assessment questionnaire.
METHODS: An anonymous voluntary online survey in English and French was
distributed to 700 active members (practicing Canadian ophthalmologists) of the
Canadian Ophthalmological Society. Data were collected regarding the potential
utility of translational aids, as well as the contents and languages that should 
be included if such aids were to be created. Level of support for translational
aids, as well as the contents and languages of potential translational aids, was 
assessed.
RESULTS: The survey response rate was 19.9% (139/700). The majority of the
respondents (130/139, 93.5%) have encountered difficulty in communicating with
patients because of language barrier, and 88.5% (123/139) would benefit from
having a list of ophthalmologic terms translated into several of Canada's most
popular languages. The top 10 languages that the respondents indicated would be
most beneficial are (in descending order): Chinese, Hindi, Spanish, Punjabi,
Italian, Portuguese, Arabic, Greek, Cree, and Vietnamese. The survey responses
provided a comprehensive list of the most useful ophthalmologic symptoms,
instructions to patients, and diagnoses to be translated. Most respondents
(120/139, 86.3%) believed that having basic information pamphlets on specific
ocular conditions translated into several languages would benefit their practice;
the top 3 conditions were cataract, glaucoma, and age-related macular
degeneration. Producing the translational aids in both paper and electronic
format was found to be the most favoured (89/139, 64.0%).
CONCLUSIONS: Canadian ophthalmologists believe they would benefit from
translational aids. The results of this survey provide a framework for the
creation of such aids.

Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc.
All rights reserved.

PMID: 26455976   [PubMed - in process]


20. Can J Ophthalmol. 2015 Oct;50(5):384-7. doi: 10.1016/j.jcjo.2015.06.007.

Immunostaining images of vitreous transthyretin amyloid.

Latasiewicz M(1), Adan A(2), Solé M(3).

Author information: 
(1)Department of Ophthalmology, Hospital Clinic of Barcelona, Barcelona, Spain.
Electronic address: mjlatasi@clinic.ub.es. (2)Department of Ophthalmology,
Hospital Clinic of Barcelona, Barcelona, Spain. (3)Department of Pathology,
Hospital Clinic of Barcelona, Barcelona, Spain.

OBJECTIVE: The purpose of this report is to present the diagnosis of familial
amyloid polyneuropathy (FAP) based on vitreous biopsy and to demonstrate
immunohistochemical images of transthyretin amyloid protein from vitreous
samples.
DESIGN: Retrospective case series.
METHODS: Retrospective review of clinical charts of patients with FAP who
underwent vitrectomy for vitreous opacities and had immunostaining performed on
the vitreous specimens.
PARTICIPANTS: Three patients were selected for the study: 2 patients had already 
been diagnosed with FAP, and in 1 of the patients the vitreous sample served to
establish the diagnosis of FAP.
RESULTS: Pathology examination of the vitreous specimens confirmed the presence
of amyloid with positive Congo red staining, and transthyretin was identified
with immunolabeling techniques. In this report, we present immunohistochemical
staining images of transthyretin deposits in the vitreous tissues.
CONCLUSIONS: Transthyretin amyloidosis is usually confirmed with positive Congo
red staining for amyloid identified by biopsy of peripheral nerves, salivary
glands, or abdominal fat. Ocular manifestation of FAP typically appears years
after the onset of the disease, and therefore eye tissue specimens usually are
not subject to diagnostic biopsies or transthyretin identification. However, in
patients with negative systemic tissue biopsies or early ocular involvement,
transthyretin identification from samples obtained during vitrectomy may be
useful in establishing the diagnosis, and we present the first
immunohistochemical images of transthyretin amyloid of vitreous origin, which
confirm the elevated deposition of the altered protein in ocular tissues in FAP.

Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc.
All rights reserved.

PMID: 26455975   [PubMed - in process]


21. Can J Ophthalmol. 2015 Oct;50(5):378-83. doi: 10.1016/j.jcjo.2015.07.008.

Removal of conjunctival cyst with high-frequency radio-wave electrosurgery.

Park J(1), Lee S(1), Suh E(2).

Author information: 
(1)Dongguk University Gyeongju Hospital, Gyeongju-si, South Korea. (2)Dongguk
University Gyeongju Hospital, Gyeongju-si, South Korea. Electronic address:
suksu57@naver.com.

OBJECTIVE: To introduce a new simple surgical approach for removal of
conjunctival cysts with high-frequency radio-wave electrosurgery.
DESIGN: Retrospective, noncomparative, interventional case series analysis.
PARTICIPANTS: Twenty-one eyes of 21 patients.
METHODS: Symptomatic conjunctival cysts, which did not show improvement despite
conventional medical management or other surgical procedures were included. The
conjunctival cysts were treated using a high-frequency radio-wave electrosurgical
unit (Ellman Surgitron; Ellman International Inc, Oceanside, N.Y.). The
conjunctiva surrounding the conjunctival cyst was grasped and lifted up using a
smooth forcep and a fine-needle electrode (Ellman Insulated Needle Electrodes
D6A; Ellman International Inc) was inserted into the cyst. A power setting of 0.5
to 1 was used for coagulation of cysts, without charring the tissue.
RESULTS: After surgery, none of the patients had recurrence of conjunctival cysts
during the follow-up period of 6 months, and symptoms also disappeared. The
surgery did not exceed 5 minutes in all cases, and subconjunctival hemorrhage was
observed in 1 case. Subconjunctival hemorrhage had completely resolved within 2
weeks and no other complications were observed.
CONCLUSIONS: A surgical approach with high-frequency radio-wave electrosurgery
successfully removed conjunctival cysts and produced improvement in symptoms.
High-frequency radio-wave surgical techniques might be a favourable alternative
to surgical treatment of conjunctival cysts.

Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc.
All rights reserved.

PMID: 26455974   [PubMed - in process]


22. Can J Ophthalmol. 2015 Oct;50(5):373-7. doi: 10.1016/j.jcjo.2014.12.012. Epub
2015 Aug 12.

Aflibercept for pigment epithelial detachment for previously treated neovascular 
age-related macular degeneration.

Major JC Jr(1), Wykoff CC(2), Croft DE(3), Wang R(3), Mariani AF(3), Lehmann
AE(3), Brown DM(1).

Author information: 
(1)Retina Consultants of Houston, Weill Cornell Medical College, Houston
Methodist Hospital. (2)Retina Consultants of Houston, Weill Cornell Medical
College, Houston Methodist Hospital. Electronic address: ccwmd@houstonretina.com.
(3)Retina Consultants of Houston, Houston, Tex.

OBJECTIVE: Assess the efficacy of intravitreal aflibercept on pigment epithelial 
detachments (PED) associated with previously treated patients with neovascular
age-related macular degeneration (AMD).
DESIGN: Retrospective study.
PARTICIPANTS: Sixty eyes.
METHODS: Patients with persistent PED who were treated with intravitreal
aflibercept (2.0 mg) with ≥2 previous injections of bevacizumab (1.25 mg) or
ranibizumab (0.5 mg) were analyzed.
RESULTS: Mean number of prior injections was 24.8 during a mean of 32 months of
management (range 3-77 months). Baseline mean PED height was 258 µm (range 80-687
µm), which decreased at 1, 6, and 12 months upon switching to aflibercept to 226 
µm (-14%, range 34-701 µm), 215 µm (-18%, range 0-666 µm), and 208 µm (-22%,
range 0-752 µm), respectively. The majority of eyes experienced a decrease in PED
height after switching to aflibercept: 50/58 (86%), 38/47 (81%), and 37/47 (79%) 
at months 1, 6, and 12, respectively. Reduction in PED height was weakly
correlated with improved visual acuity (R(2) = 0.11).
CONCLUSIONS: Intravitreal aflibercept resulted in significant reduction in PED
height in previously treated eyes with neovascular AMD.

Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc.
All rights reserved.

PMID: 26455973   [PubMed - in process]


23. Can J Ophthalmol. 2015 Oct;50(5):367-72. doi: 10.1016/j.jcjo.2015.07.006.

Transscleral fixation of single-piece foldable acrylic lens with eyelets at the
optic-haptic junction.

Yang JM(1), Yoon KC(1), Ji YS(2).

Author information: 
(1)Department of Ophthalmology, Chonnam National University Medical School and
Hospital, Gwangju, South Korea. (2)Department of Ophthalmology, Chonnam National 
University Medical School and Hospital, Gwangju, South Korea. Electronic address:
redvein@naver.com.

OBJECTIVE: To report the clinical outcomes of transscleral fixation using a
single-piece foldable acrylic intraocular lens (IOL) with eyelets at the
optic-haptic junction (enVista; Bausch & Lomb).
DESIGN: Retrospective, noncomparative case series.
PARTICIPANTS: Sixty eyes of 60 patients who underwent transscleral fixation with 
an enVista IOL were reviewed.
METHODS: Preoperative patient status, postoperative visual and refractive
outcomes, and postoperative complications were analyzed.
RESULTS: The study included 60 eyes of 60 patients (52 males, 8 females) with a
mean age of 56.65 ± 15.57 years. At final follow-up visit, the mean follow-up was
11.40 ± 4.24 months. The mean uncorrected visual acuity (logMAR) improved from
1.95 ± 0.90 to 0.85 ± 0.77 (p < 0.001), and best corrected visual acuity (logMAR)
improved from 1.11 ± 1.13 to 0.64 ± 0.70 (p = 0.006). The mean spherical
equivalent improved significantly from 6.90 ± 6.10 to 0.21 ± 2.10 D
postoperatively (p < 0.001). Complications included transient ocular hypertension
(15%), transient hypotony (7%), and hyphema (5%), but no serious complications
were observed. In all cases, the IOL remained stable and well centred.
CONCLUSIONS: Transscleral fixation using a foldable acrylic IOL with eyelets at
the optic-haptic junction can be a safe and effective alternative technique to
manage cases with broken capsular bag or weak zonular support.

Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc.
All rights reserved.

PMID: 26455972   [PubMed - in process]


24. Can J Ophthalmol. 2015 Oct;50(5):360-6. doi: 10.1016/j.jcjo.2015.07.003.

Refractive outcomes of combined phacovitrectomy and delayed cataract surgery in
retinal detachment.

Kim YK(1), Woo SJ(2), Hyon JY(3), Ahn J(4), Park KH(3).

Author information: 
(1)Department of Ophthalmology, Seoul National University College of Medicine,
Seoul National University Bundang Hospital, Seongnam; Department of
Ophthalmology, Hallym University College of Medicine, Kangdong Sacred Heart
Hospital, Seoul. (2)Department of Ophthalmology, Seoul National University
College of Medicine, Seoul National University Bundang Hospital, Seongnam.
Electronic address: sejoon1@snu.ac.kr. (3)Department of Ophthalmology, Seoul
National University College of Medicine, Seoul National University Bundang
Hospital, Seongnam. (4)Department of Ophthalmology, Seoul National University
College of Medicine, Seoul Metropolitan Government-Seoul National University
Boramae Medical Center, Seoul, South Korea.

OBJECTIVE: To compare the accuracy of refractive outcomes between combined pars
plana vitrectomy (PPV) and cataract surgery and delayed cataract surgery after
PPV in cases with rhegmatogenous retinal detachment (RD).
DESIGN: Retrospective case series.
PARTICIPANTS: Thirty-eight eyes underwent combined phacovitrectomy (combined
group) and 25 eyes underwent delayed cataract surgery after PPV (delayed group).
METHODS: RD height was measured using optical coherence tomography. Refractive
outcomes were evaluated using mean absolute error (MAE; the difference between
final refractive error and target refractive error).
RESULTS: Combined group showed significant myopic shift (mean error; -0.40 ± 1.07
vs 0.07 ± 0.56 D, p = 0.028) and large MAE (0.81 ± 0.81 vs 0.48 ± 0.29 D, p =
0.028) compared with delayed group. Multiple logistic regression analysis
revealed that only RD height was significantly associated with MAE greater than 2
D after combined surgery (in 100-µm unit, odds ratio 3.23, 95% CI 1.04-10.02, p =
0.042). RD height was also significantly correlated with the difference in axial 
length (AL) between 2 eyes of the patients (p = 0.006, r = 0.406) and the
difference in AL measured at pre- versus post-RD repair in the delayed group (p <
0.001, r = 0.774).
CONCLUSIONS: Combined phacovitrectomy in patients with rhegmatogenous RD induced 
significant myopic shift because of underestimation of AL, especially in patients
with high RD height. Thus, in cases with high temporal RD or large AL differences
between eyes, either delayed cataract surgery or combined cataract surgery using 
the contralateral AL is recommended.

Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc.
All rights reserved.

PMID: 26455971   [PubMed - in process]


25. Can J Ophthalmol. 2015 Oct;50(5):354-9. doi: 10.1016/j.jcjo.2015.06.003.

Bent versus straight tips in micropulsed longitudinal phacoemulsification.

Stagg BC(1), Gupta I(1), Cahoon J(1), Ronquillo C Jr(1), Shi D(1), Zaugg B(1),
Gardiner G(1), Barlow WR Jr(1), Pettey JH(1), Aabid Farukhi M(1), Jensen J(1),
Olson RJ(2).

Author information: 
(1)Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center,
University of Utah, Salt Lake City, Utah. (2)Department of Ophthalmology and
Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City,
Utah. Electronic address: randallj.olson@hsc.utah.edu.

OBJECTIVE: The aim of this study was to evaluate bent and straight
phacoemulsification tips to determine which tip is more efficient in removal of
lens fragments, using micropulsed longitudinal ultrasound in phacoemulsification.
DESIGN: In vitro laboratory study.
METHODS: The John A. Moran Eye Center Laboratories, University of Utah, Salt Lake
City, Utah, was the study setting. Pig lenses hardened in a manner comparable
with dense human cataracts were cut into 2-mm cubes and removed with micropulsed 
longitudinal ultrasound using settings previously shown to be optimally efficient
(6 milliseconds on and 6 milliseconds off for a bent tip). To verify this time as
most efficient for a straight tip, we also tested times of 5, 6, and 7
milliseconds time on and off. The tips were either straight or with a 20-degree
bend. Twenty cubes were used for each comparative run.
RESULTS: For the straight tip, 6 milliseconds on (1.56 ± 0.815 seconds) was
significantly more efficient than 7 milliseconds on (2.45 ± 1.56 seconds, p =
0.001) and not significantly more efficient than 5 milliseconds on (1.69 ± 0.86
seconds, p = 0.43). Five milliseconds off time (1.45 ± 0.76s) was more efficient 
than 6 milliseconds (2.06 ± 1.37 seconds, p = 0.004) and 7 milliseconds off (2.18
± 1.24s, p = 0.001). The straight tip was more efficient than the bent tip (1.38 
± 0.83 versus 2.93 ± 2.14 seconds, p = 0.006).
CONCLUSIONS: Results are contrary to accepted common belief. Micropulsed
longitudinal phacoemulsification is more efficient with a straight rather than a 
bent tip.

Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc.
All rights reserved.

PMID: 26455970   [PubMed - in process]


26. Can J Ophthalmol. 2015 Oct;50(5):350-3. doi: 10.1016/j.jcjo.2015.06.004.

Greater nondominant hand proficiency is not associated with enhanced simulated
surgical performance.

Saleh S(1), Uppal S(2), Sharma V(2).

Author information: 
(1)College of Medicine University of Saskatchewan, Saskatoon, Sask., Canada;.
Electronic address: sds673@mail.usask.ca. (2)Department of Ophthalmology,
University of Saskatchewan, Saskatoon, Sask., Canada.

OBJECTIVE: To determine whether greater nondominant hand proficiency, or
handedness approaching ambidexterity, is associated with better two-handed
anterior segment surgical outcomes.
DESIGN: Repeated-measures study.
PARTICIPANTS: Our study included 14 resident physicians from various medical
specialties, including ophthalmology, from our academic institution.
METHODS: The Eyesi surgical simulator was used to measure the surgical
proficiency of 14 resident physicians at our institution on a dominant hand,
nondominant hand, and separate bimanual task. The Edinburgh Handedness Inventory 
(EHI) was used to provide a measure of handedness for each participant.
RESULTS: The measured parameters were dominant hand, nondominant hand, and
bimanual task scores as determined by the Eyesi surgical simulator and gradients 
of handedness as determined by the Edinburgh Handedness Inventory for each
participant. Having greater nondominant hand proficiency did not enhance
two-handed surgical outcomes (p = 0.23). Surgical proficiency was greater
bimanually compared with use of the nondominant hand alone (median score 74.0 vs 
61.0; p = 0.0007), and bimanual and dominant hand surgical performances were not 
statistically significantly different from each other (median score 74.0 vs 70.5;
p = 0.17).
CONCLUSIONS: Our study shows that having greater nondominant hand proficiency is 
not a necessary trait for simulated anterior segment surgical aptitude.
Two-handed surgical outcomes are directly related to dominant hand surgical
performance but less so to the nondominant hand.

Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc.
All rights reserved.

PMID: 26455969   [PubMed - in process]


27. Can J Ophthalmol. 2015 Oct;50(5):345-9. doi: 10.1016/j.jcjo.2015.01.008.

Peripapillary RNFL thickness in nonexudative versus chronically treated exudative
age-related macular degeneration.

Yau GL(1), Campbell RJ(1), Li C(1), Sharma S(2).

Author information: 
(1)Department of Ophthalmology, Hotel Dieu Hospital, Queen's University,
Kingston, Ont. (2)Department of Ophthalmology, Hotel Dieu Hospital, Queen's
University, Kingston, Ont.. Electronic address: sanjay_sharma60@hotmail.com.

OBJECTIVE: To compare the peripapillary retinal nerve fibre layer (RNFL)
thickness in nonexudative versus exudative age-related macular degeneration (wet 
AMD) eyes treated chronically with intravitreal injections of anti-vascular
endothelial growth factor (anti-VEGF).
DESIGN: Cross-sectional study.
PARTICIPANTS: Twenty-nine patients with unilateral wet AMD with at least 12 prior
intravitreal anti-VEGF injections and 2 years of therapy were analyzed. The
fellow eye with nonexudative (dry) AMD with no prior treatment served as the
control group.
METHODS: All patients were prospectively enrolled from a single academic
subspecialist practice. Bilateral spectral-domain optical coherence tomography
(Cirrus SD-OCT; Carl Zeiss Meditec, Dublin, Calif.) of the peripapillary RNFL was
performed on all pairs of eyes. Optic nerve head (ONH) parameters were also
computed. The primary outcome was mean difference in peripapillary RNFL thickness
compared between the treated and the nontreated eyes.
RESULTS: Mean RNFL in the chronically treated eyes (95.0 [95% CI 89.8-100.2] μm) 
was significantly greater than the nontreated fellow eyes (89.9 [95% CI
85.5-94.3] μm) (p = 0.01). Quadrantic optic nerve analysis revealed the temporal 
RNFL to be greater in the treated group (p = 0.02), whereas all other locations
were similar. No significant differences were found between the 2 groups in any
ONH parameters.
CONCLUSIONS: This study demonstrated no deleterious optic nerve RNFL thinning in 
a series of wet AMD eyes with long-term repetitive exposure to intravitreal
anti-VEGF injections. Furthermore, we observed that those with wet AMD have a
relatively thickened temporal peripapillary RNFL layer, which is an important
association for all observers of optic nerve disease.

Copyright © 2015. Published by Elsevier Inc.

PMID: 26455968   [PubMed - in process]


28. Can J Ophthalmol. 2015 Oct;50(5):338-44. doi: 10.1016/j.jcjo.2015.07.005.

Trends in glaucoma surgical procedures in Ontario: 1992-2012.

Szigiato AA(1), Trope GE(2), Jin Y(3), Buys YM(4).

Author information: 
(1)Faculty of Medicine. (2)Department of Ophthalmology and Vision Sciences.
(3)Department of Ophthalmology and Vision Sciences; Dalla Lana School of Public
Health, University of Toronto, Toronto, Ont. (4)Department of Ophthalmology and
Vision Sciences. Electronic address: y.buys@utoronto.ca.

OBJECTIVE: To analyze trends in the surgical management of glaucoma in Ontario
over the past 2 decades.
DESIGN: Retrospective analysis of health records.
METHODS: Ontario Health Insurance Plan billing service claims between 1992 and
2012 were analyzed for the yearly number of glaucoma laser and incisional
surgical procedures. The yearly number of Ontarians with primary open-angle
glaucoma (POAG) was estimated by applying composite prevalence curves to
published population data and the yearly number of procedures per 1000 Ontarians 
with POAG was calculated.
RESULTS: Per 1000 people with POAG, laser trabeculoplasty (LT) rates increased
nearly 2-fold (185%) from 1992 to 2012, with the rates stabilizing between 2008
and 2012, and total glaucoma filtration procedure (GFP) rates (trabeculectomy,
aqueous shunts, and combined GFP and cataract extraction) in 2012 were similar to
those in 1992, with a peak rate noted in 1996. Shunts represented 0.9% of GFP in 
1992 and 33% in 2012. Data for combination codes billed on the same day for the
same patient were available from 2000. From 2000 to 2012 the rates of
trabeculectomy alone remained unchanged, the number of aqueous shunts alone
increased more than 5-fold, combined trabeculectomy and cataract extraction
decreased 81%, whereas combined shunts and cataract extraction increased from 6
in 2000 to 420 in 2012. Combined aqueous shunts and cataract extraction
represented 0.4% of combined cataract extractions in 2000 and 26.3% in 2012.
CONCLUSIONS: Over the past 2 decades there was an overall increase in the rate of
LT, no change in the rate of trabeculectomies, and a significant increase in
aqueous shunt surgery.

Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc.
All rights reserved.

PMID: 26455967   [PubMed - in process]