1: Indian J Ophthalmol. 2008 May-Jun;56(3):253. 

Intravitreal bevacizumab (Avastin) for the treatment of proliferative sickle
retinopathy.

Shaikh S.

Central Florida Retina Consultants, University of Central Florida, School of
Medicine, Orlando, Florida, USA. sshaikhmd@yahoo.com.

Publication Types:
    Letter

PMID: 18417840 [PubMed - in process]

2: Indian J Ophthalmol. 2008 May-June;56(3):252-253. 

Intra-cameral injection of Bevacizumab (Avastin) to treat anterior chamber
neovascular membrane in a painful blind eye.

Agarwal M, Dubey S.

Vitreoretina Services, Dr. Shroff\'s Charity Eye Hospital, 5027, Kedar Nath Road,
Daryaganj. New Delhi, India. agarwalmannii@yahoo.co.in.

Publication Types:
    LETTER

PMID: 18417839 [PubMed - as supplied by publisher]

3: Indian J Ophthalmol. 2008 May-June;56(3):250-251. 

Primary 25-guage transconjunctival sutureless vitrectomy in pseudophakic retinal
detachment.

Dubey AK, Dubey B.

Dr. Dubey\'s Retina Centre, Gwalior, MP, India. adubey56@gmail.com.

Publication Types:
    LETTER

PMID: 18417838 [PubMed - as supplied by publisher]

4: Indian J Ophthalmol. 2008 May-Jun;56(3):249-50. 

Debate on the various anti-vascular endothelial growth factor drugs.

Khalili MR, Hosseini H.

Department of Ophthalmology, Poostchi Eye Research Center, Shiraz University of
Medical Sciences, Iran. hosseinih@sums.ac.ir.

Publication Types:
    Letter

PMID: 18417837 [PubMed - in process]

5: Indian J Ophthalmol. 2008 May-Jun;56(3):247. 

Sterilization of phacoemulsification handpieces.

Thomas R.

L.V. Prasad Eye Institute, L.V. Prasad Marg, Banjara Hills, Hyderabad - 500 034,
Andhra Pradesh, India. rt@ravithomas.com.

Publication Types:
    Letter

PMID: 18417836 [PubMed - in process]

6: Indian J Ophthalmol. 2008 May-Jun;56(3):247-9. 

Right traumatic carotico-cavernous fistula with bilateral eye signs and
post-treatment right pseudo Argyll Robertson pupil.

Santhosh M, Joseph S, Doctor P.

Department of Ophthalmology, Sri Ramachandra Medical College and Research
Institute, Porur, Chennai - 600 116, Tamil Nadu, India.
marysanthoshj@yahoo.co.in.

Publication Types:
    Letter

PMID: 18417835 [PubMed - in process]

7: Indian J Ophthalmol. 2008 May-Jun;56(3):244-6. 

Isolated and silent spinal neurocysticercosis associated with pseudotumor
cerebri.

Mohapatra RN, Pattanaik JK, Satpathy SK, Joshi S.

Department of Neurosurgery, ISPAT General Hospital, Rourkela, Orissa, India.
rkl_neororabi@dataone.in.

Incidence of spinal neurocysticercosis (NCC) is rare. Isolated spinal NCC is
still rarer. We present here a case report where a young lady presented with all
the clinical features of pseudotumor cerebri (PTC), where medical treatment for
PTC failed and the presence of cysticercous in spinal canal was detected only on
the operation table, while doing a lumbo-peritoneal shunt (LP shunt) to save her
vision. Diagnosis could be confirmed only after the histopathology report was
received. She did not have any direct evidence of spinal involvement, thereby
eluding correct diagnosis. In English literature, we could not find any report
of isolated and silent spinal NCC associated with PTC. In addition, we could not
find any report of recovery of cysticercous larva through the Touhey\'s needle
injury, although this was an incidental finding. In endemic areas, isolated
spinal NCC should be suspected in patients presenting with PTC.

PMID: 18417834 [PubMed - in process]

8: Indian J Ophthalmol. 2008 May-Jun;56(3):242-4. 

Transconjunctival orbital emphysema caused by compressed air injury: A case
report.

Mathew S, Vasu U, Francis F, Nazareth C.

Department of Ophthalmology, St. Johns Medical College Hospital, Bangalore,
Karnataka, India. mathewsunu@yahoo.com.

Orbital emphysema following conjunctival tear in the absence of orbital wall
fracture, caused by air under pressure is rare. Usually orbital emphysema is
seen in facial trauma associated with damage to the adjacent paranasal sinuses
or facial bones. To the best of our knowledge, there have been only eight
reports of orbital emphysema following use of compressed air during industrial
work. The air under pressure is pushed through the subconjunctival space into
the subcutaneous and retrobulbar spaces. We present here a rare cause of orbital
emphysema in a young man working with compressed air gun. Although the emphysema
was severe, there were no orbital bone fracture and the visual recovery of the
patient was complete without attendant complications.

PMID: 18417833 [PubMed - in process]

9: Indian J Ophthalmol. 2008 May-Jun;56(3):241-2. 

Acute orbital abscess complicating deep posterior subtenon triamcinolone
injection.

Sukhija J, Dogra MR, Ram J, Ichhpujani P, Gupta A.

Department of Ophthalmology, Post Graduate Institute of Medical Education and
Research, Chandigarh, India. jagatrampgi@yahoo.co.in.

A 54-year-old diabetic female presented with orbital abscess and corneal
infiltrate 3 days after deep posterior subtenon triamcinolone acetonide
injection in her right eye. This was administered immediately after focal laser
photocoagulation for diabetic macular edema. The orbital abscess and corneal
infiltrate responded to systemic and topical antibiotics.

PMID: 18417832 [PubMed - in process]

10: Indian J Ophthalmol. 2008 May-Jun;56(3):238-40. 

Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis.

Mehta H, Mehta HB, Garg P, Kodial H.

Infiniti Eye Hospital, Jaya Mahal, French Bridge, Opera House, Mumbai - 400 007,
Maharashtra, India. drhijabmehta@gmail.com.

We report a case of Aspergillus fumigatus keratitis in a 53-year-old,
well-controlled diabetic female who did not respond to standard antifungal
treatment. She was started on topical natamycin eye drops, but the infiltrate
continued to progress. Topical amphotericin B and systemic ketoconazole was
added, however, there was no response and the infiltrate increased further. She
was then switched to topical and systemic voriconazole. Steady resolution of the
infiltrate was noted within 2 weeks of therapy.

PMID: 18417831 [PubMed - in process]

11: Indian J Ophthalmol. 2008 May-Jun;56(3):236-8. 

Descemet\'s membrane detachment caused by inadvertent vancomycin injection.

Bhattacharjee H, Bhattacharjee K, Medhi J, Altaf A.

Sri Sankardeva Nethralaya, Guwahati, Assam, India. jmedhi@rediffmail.com.

Descemet\'s membrane detachment is a condition with a wide range of etiologies.
The most common cause is a localized detachment occurring after cataract
surgery. We report a case of vancomycin injection-induced Descemet\'s membrane
detachment as a complication following a routine cataract surgery and its
management.

PMID: 18417830 [PubMed - in process]

12: Indian J Ophthalmol. 2008 May-Jun;56(3):234-5. 

Giant hanging melanoma of the eyelid skin.

Pai RR, Kini H, Kamath SG, Kumar S.

Department of Pathology, Kasturba Medical College, Mangalore, India.
pairadharam@yahoo.co.in.

Cutaneous melanoma of the eyelid is a rare entity. We present a 53-year-old male
who had a nevus on the left upper eyelid skin since childhood, which transformed
into a huge ulcerated hanging mass in the same region. Excision of the mass was
done and histopathology confirmed the diagnosis of nodular malignant melanoma. A
small preauricular lymph node showed metastatic melanoma on fine needle
aspiration cytology.

PMID: 18417829 [PubMed - in process]

13: Indian J Ophthalmol. 2008 May-Jun;56(3):232-4. 

Recurrent neovascularization of the disc in sympathetic ophthalmia.

Sampangi R, Venkatesh P, Mandal S, Garg SP.

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of
Medical Sciences, New Delhi - 110 029, India. venkyprao@yahoo.com.

Sympathetic ophthalmia following parsplana vitrectomy is a known complication.
We describe here a case of recurrent disc neovascularization in a patient of
sympathetic ophthalmia. It promptly responded to steroids initially but later
recurred with inflammation.

PMID: 18417828 [PubMed - in process]

14: Indian J Ophthalmol. 2008 May-Jun;56(3):230-2. 

Sudoriferous cyst of the orbit of adult origin after trauma.

Mehta A, Rao A, Khanna A.

ICARE Hospital, Noida, Uttar Pradesh, India. mehtanjali@gmail.com.

A rare case of sudoriferous cyst of the orbit occurring in an adult, who had
facial trauma, is reported. Several factors suggest its adult onset. The only
other case reported in an adult is of presumed childhood origin. Very few
congenital cases have been reported. A 65-year-old lady presented with recent
onset of left-sided ptosis and a painless mass below the left supraorbital
margin. The patient had traumatic ptosis after a road traffic accident 13 years
ago. The ptosis was surgically repaired, which resulted in symmetrical palpebral
apertures. Computed tomographic scan revealed a well-defined cystic mass in the
anterior orbit. The mass was removed in toto by anterior orbitotomy.
Histopathological examination revealed a single cyst lined by double-layered
cuboidal epithelium in some areas and transitional epithelium at others. A
periodic acid Schiff (PAS) positive, diastase-resistant glycocalyx lined the
inner epithelium. Apical snouting suggested an apocrine nature. This confirmed a
diagnosis of sudoriferous cyst.

PMID: 18417827 [PubMed - in process]

15: Indian J Ophthalmol. 2008 May-Jun;56(3):228-30. 

Calculating graft size and position in rotational corneal autografting: A
simplified approach.

Rao SK, Lam DS.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong
Kong, Hong Kong Special Administrative Region, P. R. China, .
srinikrao@gmail.com.

In eyes with eccentric corneal opacities partially involving the pupillary area,
using a rotational corneal autograft, can help restore vision without the
immunological complications associated with allografts. In this report, we
describe a simple intraoperative method for determining trephine size and
placement for rotational corneal autografting. This surgical approach helps in
the planning and execution of rotational corneal autografting, to obtain good
outcomes.

PMID: 18417826 [PubMed - in process]

16: Indian J Ophthalmol. 2008 May-Jun;56(3):226-7. 

Periocular necrotizing fasciitis associated with kerato-conjunctivitis and
treated with medical management: A case report.

Shome D, Jain V, Jayadev C, Shah K, Natarajan S.

Department of Ophthalmic and Facial Plastic Surgery orbital Diseases and Ocular
Oncology, Aditya Jyot Eye Hospital Pvt Ltd, Mumbai; Department of Ocular
Oncology, Tata Memorial Centre, Mumbai, India. debraj_shome@yahoo.com.

We report a 25-year-old systemically healthy male who presented with periocular
necrotizing fasciitis (NF) in the left eyelid. This was associated with the
presence of immunologically mediated marginal kerato-conjunctivitis, in the same
eye. This potentially dangerous lid infection and the associated ocular surface
infection resolved successfully, with medical management. We report this case to
highlight the successful conservative management of periocular NF and the
hitherto unreported anterior segment involvement.

PMID: 18417825 [PubMed - in process]

17: Indian J Ophthalmol. 2008 May-Jun;56(3):218-25. 

Practical approach to medical management of glaucoma.

Parikh RS, Parikh SR, Navin S, Arun E, Thomas R.

LV Prasad Eye Institute, Hyderabad, Andhra Pradesh, India. drparikhs@gmail.com.

Primary open angle glaucoma (POAG) is usually a chronic, slowly progressive
disease. At present, all resources are directed towards reduction of intraocular
pressure (IOP), the only known causal and treatable risk factor for glaucoma,
and medical management is frequently the first choice in most cases. With the
introduction of innovative tools for early diagnosis and newer medications for
treatment, decision-making in diagnosis and treatment of glaucoma has become
more complex. The philosophy of glaucoma management is to preserve the visual
function and quality of life (QOL) of the individual with minimum effects on QOL
in terms of cost, side effects, treatment regime, follow-up schedules as well as
socioeconomic burden. Our aim should be not to treat just the IOP, optic disc or
visual field, but to treat the patient as a whole so as to provide maximum
benefit with minimal side effects. In this article, we describe the scientific
approach to medical management, mainly of POAG.

PMID: 18417824 [PubMed - in process]

18: Indian J Ophthalmol. 2008 May-Jun;56(3):216-7. 

First aid for complications of infectious keratitis.

Agrawal V.

Clear Vision Eye Center, Santacruz (W), Mumbai - 400 054, Maharashtra, India.
drvinay.agrawal@gmail.com.

Infectious keratitis is a fairly common entity in India. However while paying
attention to the primary entity, the associated events may be overlooked.
Enhanced pain usually suggests a worsening of the condition or development of
associated problems like secondary glaucoma. However, contrary to logic, a
sudden decrease in pain is also liley to suggest a worsening, e.g. perforation
of the corneal ulcer. Various such problems with their management are outlined.

PMID: 18417823 [PubMed - in process]

19: Indian J Ophthalmol. 2008 May-Jun;56(3):210-5. 

Medical management approach to infectious keratitis.

Gokhale NS.

Gokhale Eye Hospital and Eyebank, Anant Building, Gokhale Road (S), Dadar West,
Mumbai-400 028, India. gokhlay@vsnl.com.

This section provides guidelines on medical therapy of patients with infectious
keratitis. In addition to initial empirical therapy, preferred medications, once
the organisms responsible are isolated, are discussed. Atypical mycobacterial
keratitis following lasik is described. General guidelines for supportive
therapy and follow-up, of these patients are presented. Clinical response to
treatment and indications for intervention are discussed. Possible causes and
approach to cases refractory to medical therapy are discussed.

PMID: 18417822 [PubMed - in process]

20: Indian J Ophthalmol. 2008 May-Jun;56(3):205-9. 

Investigative modalities in infectious keratitis.

Gupta N, Tandon R.

RP Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New
Delhi - 110 029, India. radhika_tan@yahoo.com.

Standard recommended guidelines for diagnosis of infectious keratitis do exist.
Based on an extensive Medline literature search, the various investigative
modalities available for aiding the diagnosis of microbial keratitis have been
reviewed and described briefly. Preferred practice patterns have been outlined
and the importance of routine pre-treatment cultures in the primary management
of infectious keratitis has been highlighted. Corneal scraping, tear samples and
corneal biopsy are few of the specimens needed to carry out the investigative
procedures for diagnosis and for initiating therapy in cases of microbial
keratitis. In bacterial, fungal and amoebic keratitis, microscopic examination
of smears is essential for rapid diagnosis. Potassium hydroxide (KOH) wet mount,
Gram\'s stain and Giemsa stain are widely used and are important for clinicians
to start empirical therapy before microbial culture results are available. The
usefulness of performing corneal cultures in all cases of suspected infectious
keratitis has been well established. In cases of suspected viral keratitis,
therapy can be initiated on clinical judgment alone. If a viral culture is
needed, scrapings should directly be inoculated into the viral transport media.
In vivo confocal microscopy is a useful adjunct to slit lamp bio-microscopy for
supplementing diagnosis in most cases and establishing early diagnosis in many
cases of non-responding fungal and amoebic keratitis. This is a non-invasive,
high resolution technique which allows rapid detection of Acanthamoeba cysts and
trophozoites and fungal hyphae in the cornea long before laboratory cultures
give conclusive results. Other new modalities for detection of microbial
keratitis include molecular diagnostic techniques like polymerase chain
reaction, and genetic finger printing by pulsed field gel electrophoresis.

PMID: 18417821 [PubMed - in process]

21: Indian J Ophthalmol. 2008 May-Jun;56(3):200-4. 

Distinguishing infective versus noninfective keratitis.

Srinivasan M, Mascarenhas J, Prashanth CN.

Department of Cornea and External Eye Diseases, Aravind Eye Hospitals, Madurai -
625 020, Tamil Nadu, India. prashanthcndoctor@gmail.com.

For the purpose of this symposium, the term "keratitis" implies suppurative
nonviral and viral keratitis. Corneal ulcers have been described in ancient
literature. But even today, despite the availability of a wide range of newer
antimicrobials and new diagnostic techniques, infective keratitis continues to
pose a diagnostic and therapeutic challenge. This article focuses on the key
diagnostic clinical features of the most common organisms causing infective
keratitis - bacteria, fungi, viruses, nocardia and acanthamoeba - in India.
While the clinical features in some cases are fairly straightforward, most cases
challenge the clinician. We describe the salient clinical features which can
help arrive at a diagnosis to begin appropriate treatment immediately, prior to
the laboratory report.

PMID: 18417820 [PubMed - in process]

22: Indian J Ophthalmol. 2008 May-Jun;56(3):195-9. 

Transconjunctival penetration of mitomycin C.

Velpandian T, Sihota R, Sinha A, Gupta V.

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of
Medical Sciences, New Delhi, India. drankursinha@yahoo.co.uk.

Aims: The study was performed to estimate transconjunctival penetration of
mitomycin C (MMC) to Tenon\'s tissue following application over the intact
conjunctiva before routine trabeculectomy. Settings and Design:
Institution-based case series. Materials and Methods: In 41 eyes of 41 patients,
MMC (0.4 mg/ml for 3 min) was applied over the intact conjunctiva before
beginning trabeculectomy. Tenon\'s capsule directly beneath the site of
application was excised during trabeculectomy and was homogenized, centrifuged
and MMC concentrations were analyzed using high-performance liquid
chromatography (HPLC). Statistical Analysis Used: Statistical analysis was
performed using stata0 8.0 version software (STATA Corporation, Houston, TX,
USA). In this study, P -values less than 0.05 were considered as statistically
significant. Results: The average weight of the sample of Tenon\'s tissue excised
was 5.51 +/- 4.42 mg (range: 0.9-17.1) and the average estimated MMC
concentration found to be present in Tenon\'s tissue using HPLC was 18.67 +/-
32.36 x 10-6 moles/kg of the tissue (range: 0.38-197.05 x 10-6 ). In 36 of the
41 patients (87.80%), the MMC concentration reached above 2 x 10-6 moles/kg of
the tissue concentration required to inhibit human conjunctival fibroblasts.
Conclusions: Mitomycin C does permeate into the subconjunctival tissue after
supraconjunctival application for 3 min. Application of MMC over the conjunctiva
may be a useful alternative to subconjunctival or subscleral application during
routine trabeculectomy and as an adjunct for failing blebs.

PMID: 18417819 [PubMed - in process]

23: Indian J Ophthalmol. 2008 May-Jun;56(3):188-94. 

An observational study of the proceedings of the All India Ophthalmological
Conference, 2000 and subsequent publication in indexed journals.

Dhaliwal U, Kumar R.

Department of Ophthalmology, University College of Medical Sciences and GTB
Hospital, New Delhi - 110 095, India. upreetdhaliwal@yahoo.com.

Aims: To determine the quality of reporting in the proceedings of the All India
Ophthalmological Conference (AIOC) 2000, subsequent rate of publication in an
indexed journal and differences between the proceedings and the journal version
of these papers. Design: Observational study. Materials and Methods: All papers
presented at the AIOC 2000 were retrieved from the proceedings and assessed for
completeness of reporting. To determine the subsequent full publication, a
Medline search was performed as of January 2007; consistency between the
proceedings paper and the final publication was evaluated. Statistical analysis:
Chi square and Fisher\'s exact tests were used to compare publication rates based
on geographical location, subspecialty and study design; Student\'s t -test was
used to compare differences based on the number of authors and sample size.
Results: Two hundred papers were retrieved; many failed to include study dates,
design or statistical methods employed. Thirty-three (16.5%) papers were
subsequently published in indexed journals by January 2007. The published
version differed from the proceedings paper in 27 (81.8%) instances, mostly
relating to changes in author name, number or sequence. Conclusions: The overall
quality of reporting of scientific papers in the proceedings of the AIOC 2000
was inadequate and many did not result in publication in an indexed journal.
Differences between the published paper in journals and in proceedings were seen
in several instances. Ophthalmologists should be cautious about using the
information provided in conference proceedings in their ophthalmic practice.

PMID: 18417818 [PubMed - in process]

24: Indian J Ophthalmol. 2008 May-Jun;56(3):178-87. 

Diabetic retinopathy: An update.

Singh R, Ramasamy K, Abraham C, Gupta V, Gupta A.

Department of Ophthalmology, Postgraduate Institute of Medical Education and
Research, Chandigarh, India. eyepgi@sify.com.

Diabetes mellitus is a major cause of avoidable blindness in both the developing
and the developed countries. Significant technological advances have taken place
to improve the diagnostic accuracy of diabetic retinopathy. In the last three
decades, the treatment strategies have been revised to include, besides laser
photocoagulation, early surgical interventions and pharmacotherapies.

PMID: 18417817 [PubMed - in process]

25: Indian J Ophthalmol. 2008 May-Jun;56(3):177. 

Statement on publishing clinical trials in Indian biomedical journals.

Satyanarayana K, Sharma A, Parikh P, Vijayan VK, Sahu DK, Nayak BK, Gulati RK,
Parikh MN, Singh PP, Bavdekar SB, Sreehari U, Sahni P.

Indian Journal of Ophthalmology, India. editor@ijo.in.

PMID: 18417816 [PubMed - in process]

26: Indian J Ophthalmol. 2008 May-Jun;56(3):175-6. 

Marching ahead with clinical trial registration.

Nayak BK.

P. D. Hinduja National Hospital and Medical Research Centre, Veer Savarkar Marg,
Mahim, Mumbai - 400 016, India. ijo.editor@gmail.com.

PMID: 18417815 [PubMed - in process]